Evidence map›Paper›PMID 12946291›Full record

ReviewCurrent pain and headache reports2003

Convergence of cervical and trigeminal sensory afferents.

Elcio J Piovesan, Pedro A Kowacs, Michael L Oshinsky

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04317937 (The Effects Of Jaw Sensorimotor System In The Treatment Of Neck Pain And Dysfunction), which is not on this map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04317937 nacompletednot on this mapstarted 2018, after this paper: background citation

The Effects Of Jaw Sensorimotor System In The Treatment Of Neck Pain And Dysfunction

TypeinterventionalSponsorUniversity of LahoreRan2018 to 2022Enrolled80ConditionsNeck Pain, PHYSIOTHERAPY, JAWArmsJaw opening-closing movements, Specific Active exercises, Exercise Therapy, Supportive Treatment
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elcio J PiovesanJorge Manços do Nascimento Teixeira 868, São José dos Pinhais, 83005-500 Brazil. piovesan1@hotmail.com
Pedro A Kowacs
Michael L Oshinsky

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cranial nociceptive perception shows a distinct topographic distribution, with the trigeminal nerve receiving sensory information from the anterior portions of the head, the greater occipital nerve, and branches of the upper cervical roots in the posterior regions. However, this distribution is not respected during headache attacks, even if the etiology of the headache is specific for only one nerve. Nociceptive information from the trigeminal and cervical territories activates the neurons in the trigeminal nucleus caudalis that extend to the C2 spinal segment and lateral cervical nucleus in the dorsolateral cervical area. These neurons are classified as multimodal because they receive sensory information from more than one afferent type. Clinically, trigeminal activation produces symptoms in the trigeminal and cervical territory and cervical activation produces symptoms in the cervical and trigeminal territory. The overlap between the trigeminal nerve and cervical is known as a convergence mechanism. For some time, convergence mechanisms were thought to be secondary to clinical observations. However, animal studies and clinical evidence have expanded our knowledge of convergence mechanisms. In this paper, the role of convergence mechanisms in nociceptive physiology, physiopathology of the headaches, clinical diagnosis, and therapeutic conduct are reviewed.

Indexed as

ElectrophysiologyGenes, fosHeadacheHumansHypoglossal NerveImmunohistochemistryNeurons, AfferentNociceptorsProto-Oncogene Proteins c-fosSensationSpinal NervesTrigeminal NerveProto-Oncogene Proteins c-fos

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.