ArticleJournal of clinical pathology2003
Gemella bacteraemia characterised by 16S ribosomal RNA gene sequencing.
Article in Journal of clinical pathology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 84 citations in OpenAlex.
- Article
- Emergency Double Valve Replacement for Ruptured Mitral Valve Aneurysm and Annular Abscess Caused by Gemella Morbillorum Endocarditis in a Patient with Bicuspid Aortic Valve: A Case Report.Surgical case reports · 2026Article
- Integrative analysis of microbial 16S gene and shotgun metagenomic sequencing data improves statistical efficiency in testing differential abundance.Journal of the American Statistical Association · 2025Article
- Antimicrobial Susceptibility to 27 Drugs and the Molecular Mechanisms of Macrolide, Tetracycline, and Quinolone Resistance inAntibiotics (Basel, Switzerland) · 2023Article
- A Rare Pathogen of Bones and Joints: A Systematic Review of Osteoarticular Infections Caused byJournal of clinical medicine research · 2023Review
- Microbiota Phenotype Promotes Anastomotic Leakage in a Model of Rats with Ischemic Colon Resection.Microorganisms · 2023Article
- Acute Hematogenous Periprosthetic Hip Infection byTropical medicine and infectious disease · 2022Article
- Article
- Article
- Multi-valvular infective endocarditis fromBMJ case reports · 2021Article
- Gemella haemolysans inhibits the growth of the periodontal pathogen Porphyromonas gingivalis.Scientific reports · 2021Article
- The First Case Report of Mediastinal Abscess Caused by Gemella bergeri.Internal medicine (Tokyo, Japan) · 2021Article
- A Case Report ofInfection and drug resistance · 2021Article
- The Versatility of Opportunistic Infections Caused byFrontiers in microbiology · 2020Article
- Article
- Use of 16S rRNA gene for identification of a broad range of clinically relevant bacterial pathogens.PloS one · 2015Article
- Gemella morbillorum prosthetic aortic valve endocarditis.BMJ case reports · 2014Article
- Molecular diagnosis of bacterial infective endocarditis in tabriz, azerbaijan.Journal of cardiovascular and thoracic research · 2013Article
- The influence of iron availability on human salivary microbial community composition.Microbial ecology · 2012Article
- Biotransformation of puerarin into puerarin-6″-O-phosphate by Bacillus cereus.Journal of industrial microbiology & biotechnology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo define epidemiology, clinical disease, and outcome of gemella bacteraemia by 16S rRNA gene sequencing. To examine the usefulness of the Vitek, API, and ATB systems in identifying two gemella species.
methodsAll alpha haemolytic streptococci other than Streptococcus pneumoniae isolated from blood cultures during a six year period were identified by conventional biochemical methods, the Vitek system, and the API system. 16S rRNA gene sequencing was performed on all isolates identified by both kits as gemella with >or= 95% confidence or by either kit as any bacterial species with < 95% confidence. The ATB expression system was used to identify the two isolates that were defined as gemella species by 16S rRNA gene sequencing.
resultsOf the 302 alpha haemolytic streptococci other than S pneumoniae isolated, one was identified as Gemella morbillorum, and another as Gemella haemolysans by 16S rRNA gene sequencing. The patient with monomicrobial G morbillorum bacteraemia was a 66 year old man with community acquired infective endocarditis with septic thromboemboli. The patient with G haemolysans bacteraemia was a 41 year old woman with hospital acquired polymicrobial bacteraemia during the neutropenic period of an autologous bone marrow transplant for non-Hodgkin's lymphoma, the first case of its kind in the English literature. The API and ATB expression systems only identified the second strain as G haemolysans at 94% and 99% confidence, respectively, whereas the Vitek system identified none of the two strains correctly at > 70% confidence.
conclusionsGemella bacteraemia is uncommon. 16S rRNA gene sequencing is the method of choice for identification of gemella and gemella-like isolates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.