ArticleBiophysical journal2003
Low-frequency modes of peptides and globular proteins in solution observed by ultrafast OHD-RIKES spectroscopy.
Article in Biophysical journal, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 125 citations in OpenAlex.
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- Dimensional Design for Surface-Enhanced Raman Spectroscopy.ACS materials Au · 2022Review
- Protein-Ligand Binding Molecular Details Revealed by Terahertz Optical Kerr Spectroscopy: A Simulation Study.JACS Au · 2021Article
- Protein Hydration in a Bioprotecting Mixture.Life (Basel, Switzerland) · 2021Article
- Tracking Ultrafast Structural Dynamics by Time-Domain Raman Spectroscopy.Journal of the American Chemical Society · 2021Article
- Low-Frequency (Gigahertz to Terahertz) Depolarized Raman Scattering OffThe journal of physical chemistry. B · 2020Article
- Shape-preserving elastic solid models of macromolecules.PLoS computational biology · 2020Article
- Why Proteins are Big: Length Scale Effects on Equilibria and Kinetics.The protein journal · 2019Review
- New Method to Study the Vibrational Modes of Biomolecules in the Terahertz Range Based on a Single-Stage Raman Spectrometer.ACS omega · 2017Article
- Terahertz Frequency Spectroscopy to Determine Cold Shock Protein Stability upon Solvation and Evaporation - A Molecular Dynamics Study.IEEE transactions on terahertz science and technology · 2017Article
- Vibrational resonance, allostery, and activation in rhodopsin-like G protein-coupled receptors.Scientific reports · 2016Article
- Observation of coherent delocalized phonon-like modes in DNA under physiological conditions.Nature communications · 2016Article
- Ultrafast charge transfer in nickel phthalocyanine probed by femtosecond Raman-induced Kerr effect spectroscopy.Journal of the American Chemical Society · 2014Article
- THz time scale structural rearrangements and binding modes in lysozyme-ligand interactions.Journal of biological physics · 2014Article
- Low-frequency mode activity of heme: femtosecond coherence spectroscopy of iron porphine halides and nitrophorin.Journal of the American Chemical Society · 2008Article
- Terahertz spectroscopy of bacteriorhodopsin and rhodopsin: similarities and differences.Biophysical journal · 2008Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The low-frequency (1-200 cm(-1)) vibrational spectra of peptides and proteins in solution have been investigated with ultrafast optical heterodyne-detected Raman-induced Kerr-effect spectroscopy (OHD-RIKES). Spectra have been obtained for di-L-alanine (ALA(2)) and the alpha-helical peptide poly-L-alanine (PLA) in dichloroacetic acid solution. The poly-L-alanine spectrum shows extra amplitude compared to the di-L-alanine spectrum, which can be explained by the secondary structure of the former. The globular proteins lysozyme, alpha-lactalbumin, pepsin, and beta-lactoglobulin in aqueous solution have been studied to determine the possible influence of secondary or tertiary structure on the low-frequency spectra. The spectra of the globular proteins have been analyzed in terms of three nondiffusive Brownian oscillators. The lowest frequency oscillator corresponds to the so-called Boson peak observed in inelastic neutron scattering (INS). The remaining two oscillators are not observed in inelastic neutron scattering, do therefore not involve significant motion of hydrogen atoms, and may be associated with delocalized backbone torsions.
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