ArticleBiophysical journal2003
Intermolecular interactions in dry and rehydrated pure and mixed bilayers of phosphatidylcholine and digalactosyldiacylglycerol: a Fourier transform infrared spectroscopy study.
Article in Biophysical journal, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 110 citations in OpenAlex.
- Human meibum lipid conformation and thermodynamic changes with meibomian-gland dysfunction.Investigative ophthalmology & visual science · 2011Trial
- Topical azithromycin therapy for meibomian gland dysfunction: clinical response and lipid alterations.Cornea · 2010Trial
- Glycolipids slow interfacial proton migration while preserving surface proton retention.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Direct Correlation of Levels of Meibum Cholesteryl Esters, Hydrocarbon Chain Saturation, and Protein With Lipid Structure, in Relation to Age and Dry Eye.Investigative ophthalmology & visual science · 2026Article
- Plant-derived nanovesicles: Promising therapeutics and drug delivery nanoplatforms for brain disorders.Fundamental research · 2025Review
- Platycodon grandiflorum-derived extracellular vesicles suppress triple-negative breast cancer growth by reversing the immunosuppressive tumor microenvironment and modulating the gut microbiota.Journal of nanobiotechnology · 2025Article
- Limits and Prospects of Molecular Fingerprinting for Phenotyping Biological Systems Revealed throughAnalytical chemistry · 2023Article
- Mechanism Study on Nanoparticle Negative Surface Charge Modification by Ascorbyl Palmitate and Its Improvement of Tumor Targeting Ability.Molecules (Basel, Switzerland) · 2022Article
- Aloe derived nanovesicle as a functional carrier for indocyanine green encapsulation and phototherapy.Journal of nanobiotechnology · 2021Article
- Stabilization of Dry Sucrose Glasses by Four LEA_4 Proteins fromBiomolecules · 2021Article
- Concentration dependent cholesteryl-ester and wax-ester structural relationships and meibomian gland dysfunction.Biochemistry and biophysics reports · 2020Article
- Organometallic Complex Strongly Impairs Chikungunya Virus Entry to the Host Cells.Frontiers in microbiology · 2020Article
- Structural properties and enzyme stabilization function of the intrinsically disordered LEA_4 protein TdLEA3 from wheat.Scientific reports · 2019Article
- Folding and Lipid Composition Determine Membrane Interaction of the Disordered Protein COR15A.Biophysical journal · 2018Article
- Rapamycin-loaded Immunoliposomes Functionalized with Trastuzumab: A Strategy to Enhance Cytotoxicity to HER2-positive Breast Cancer Cells.Anti-cancer agents in medicinal chemistry · 2017Article
- Edible Ginger-derived Nano-lipids Loaded with Doxorubicin as a Novel Drug-delivery Approach for Colon Cancer Therapy.Molecular therapy : the journal of the American Society of Gene Therapy · 2016Article
- Investigating how the attributes of self-associated drug complexes influence the passive transport of molecules through biological membranes.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2016Article
- Functional characterization of selected LEA proteins from Arabidopsis thaliana in yeast and in vitro.Planta · 2014Article
- Interactions of the amphiphiles arbutin and tryptophan with phosphatidylcholine and phosphatidylethanolamine bilayers in the dry state.BMC biophysics · 2013Article
- Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glycolipids are an important part of almost all biological membranes. Their effects on membrane structure and their interactions with phospholipids, however, have not been extensively studied so far. We have investigated the phase behavior and intermolecular interactions in dry and rehydrated bilayers made from the phospholipid egg phosphatidylcholine (EPC) and the plant chloroplast glycolipid digalactosyldiacylglycerol (DGDG), or from a mixture (1:1) of these lipids, using Fourier transform infrared spectroscopy. We show that there are extensive interactions between EPC and DGDG in mixed membranes, and also between DGDG molecules in pure DGDG membranes, involving sugar OH groups and C[double bond]O, P[double bond]O, and choline moieties in dry membranes. These interactions persist to a certain degree even after rehydration. We present evidence that these interactions influence the mixing behavior in phosphatidylcholine/DGDG membranes and also the phase behavior of both EPC/DGDG and pure DGDG membranes in the dry state.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.