Evidence map›Paper›PMID 12943271›Full record

ArticleTheoretical medicine and bioethics2003

The ethics of type 1 diabetes prediction and prevention research.

Lainie Friedman Ross

Abstract read
PubMed Publisher
In one paragraph

Article in Theoretical medicine and bioethics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Children, longitudinal studies, and informed consent.Medicine, health care, and philosophy · 2005
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Lainie Friedman RossDepartment of Pediatrics, University of Chicago, IL 60637, USA. lross@uchicago.edu

Funding

CHILDREN IN MEDICAL RESEARCH: ETHICAL&POLICY CHALLENGESG13LM007472 · NLM · UNIVERSITY OF CHICAGO · PI ROSS, LAINIE FRIEDMAN · 2001 to 2003
$227k
NLM NIH HHS 1 G13 LM07472-01
6 · The paper itself

Abstract

There are approximately one million cases of type 1 diabetes in the US, and the incidence is increasing worldwide. Given that two-thirds of cases present in childhood, it is critical that prediction and prevention research involve children. In this article, I examine whether current research methodologies conform to the ethical guidelines enumerated by the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, and adopted into the federal regulations that protect research subjects. I then offer two policy recommendations to help researchers design studies that conform to these ethical requirements.

Indexed as

Ethics, ResearchChildDiabetes Mellitus, Type 1Guidelines as TopicHuman ExperimentationHumansPediatricsPolicy MakingRisk AssessmentUnited StatesBiomedical and Behavioral ResearchNational Commission for the Protection of Human Subjects

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.