ArticleBritish journal of cancer2003
Functional analysis of the actin-binding protein, tropomyosin 1, in neuroblastoma.
Article in British journal of cancer, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 37 citations in OpenAlex.
- Research Advances in the Role of the Tropomyosin Family in Cancer.International journal of molecular sciences · 2023Review
- Mechanosensitive expression of the mesenchymal subtype marker connective tissue growth factor in glioblastoma.Scientific reports · 2022Article
- The remodelling of actin composition as a hallmark of cancer.Translational oncology · 2021Review
- Tropomyosin Tpm 2.1 loss induces glioblastoma spreading in soft brain-like environments.Journal of neuro-oncology · 2019Article
- Downregulated Expression of Tropomyosin 1 in Intrahepatic Cholangiocarcinoma: A Predictor of Recurrence and Prognosis.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Tropomyosin-1 promotes cancer cell apoptosis via the p53-mediated mitochondrial pathway in renal cell carcinoma.Oncology letters · 2018Article
- New insights into the regulation of the actin cytoskeleton by tropomyosin.International review of cell and molecular biology · 2010Review
- Screening of potential biomarkers for cholangiocarcinoma by integrated analysis of microarray data sets.Cancer gene therapyArticle
- Interior decoration: tropomyosin in actin dynamics and cell migration.Cell adhesion & migrationReview
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tropomyosin 1 (TM1) is downregulated in a number of transformed cell types, and exogenous expression of TM1 can restore actin organisation and reverse cellular transformation. We find that TM1 is also downregulated in human neuroblastoma cell lines, correlating with increasing malignancy. However, exogenous TM1 does not restore actin cytoskeleton organisation in neuroblastoma cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.