ArticleInternational journal of legal medicine2003
Rapid screening of mtDNA coding region SNPs for the identification of west European Caucasian haplogroups.
Article in International journal of legal medicine, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Review
- Forensically relevant SNaPshotInternational journal of legal medicine · 2017Review
- Multiplex minisequencing screening for PTC genotype associated with bitter taste perception.Molecular biology reports · 2014Article
- Mass spectrometric base composition profiling: Implications for forensic mtDNA databasing.Forensic science international. Genetics · 2013Article
- The tooth for molecular analysis and identification : a forensic approach.The Journal of forensic odonto-stomatology · 2012Article
- Current genetic methodologies in the identification of disaster victims and in forensic analysis.Journal of applied genetics · 2012Review
- Multiplex genotyping system for efficient inference of matrilineal genetic ancestry with continental resolution.Investigative genetics · 2011Article
- Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients.American journal of human genetics · 2010Article
- Ancient DNA from European early neolithic farmers reveals their near eastern affinities.PLoS biology · 2010Article
- Multiplex analysis of mitochondrial DNA pathogenic and polymorphic sequence variants.Biological chemistry · 2010Article
- Forensic and phylogeographic characterization of mtDNA lineages from northern Thailand (Chiang Mai).International journal of legal medicine · 2009Article
- Genetic identification of putative remains of the famous astronomer Nicolaus Copernicus.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Mitochondrial haplogroups and control region polymorphisms are not associated with prostate cancer in Middle European Caucasians.PloS one · 2009Article
- Assignment of unknown persons to their geographical origin by determination of stable isotopes in hair samples.International journal of legal medicine · 2009Article
- A rapid mtDNA assay of 22 SNPs in one multiplex reaction increases the power of forensic testing in European Caucasians.International journal of legal medicine · 2008Article
- Timing and deciphering mitochondrial DNA macro-haplogroup R0 variability in Central Europe and Middle East.BMC evolutionary biology · 2008Article
- Minisequencing mitochondrial DNA pathogenic mutations.BMC medical genetics · 2008Article
- Mitochondrial DNA polymorphisms and haplogroups in Parkinson's disease and control individuals with a similar genetic background.Journal of human genetics · 2008Article
- First successful assay of Y-SNP typing by SNaPshot minisequencing on ancient DNA.International journal of legal medicine · 2007Article
- STRs vs. SNPs: thoughts on the future of forensic DNA testing.Forensic science, medicine, and pathology · 2007Article
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3 authors.
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Abstract
This work presents a selection of 16 SNPs from the coding region of the human mitochondrial DNA. The selected markers are used for the assignment of individuals to one of the nine major European Caucasian mitochondrial haplogroups. The selected SNPs are targeted in two multiplex systems, via the application of the SNaPshot kit, a multiplex method based on the dideoxy single-base extension of unlabeled oligonucleotide primers. The method is conceived as a rapid screening technique prior to sequencing analysis, in order to eliminate multiple suspects from an inquiry or to discriminate between stains in a high volume casework example. Moreover, the ability to assign an unknown sample to an mtDNA type of known Caucasian origin could be of probative value in some investigations. A database of 277 Austrian Caucasians has been constructed, and the probability of a chance match between two unrelated individuals is calculated as 11.4%. This novel multiplex PCR amplification and typing system for mtDNA coding region SNPs promises to be a convenient and informative new DNA profiling system in the forensic field.
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