SynthesisOccupational and environmental medicine2003
Occupation related pesticide exposure and cancer of the prostate: a meta-analysis.
Synthesis in Occupational and environmental medicine, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Modifiable risk factors for prostate cancer in low- and lower-middle-income countries: a systematic review and meta-analysis.Prostate cancer and prostatic diseases · 2022Pooled it
- Body concentrations of persistent organic pollutants and prostate cancer: a meta-analysis.Environmental science and pollution research international · 2015Pooled it
- Prostate cancer and driving occupations: could whole body vibration play a role?International archives of occupational and environmental health · 2009Pooled it
- Prostate cancer among pesticide applicators: a meta-analysis.International archives of occupational and environmental health · 2004Pooled it
- Article
- The Level of Adherence to Organic Food Consumption and Risk of Cancer: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2025Review
- Impact of occupational pesticide exposure assessment method on risk estimates for prostate cancer, non-Hodgkin's lymphoma and Parkinson's disease: results of three meta-analyses.Occupational and environmental medicine · 2022Review
- A cohort study of banana plantation workers in the French West Indies: first mortality analysis (2000-2015).Environmental science and pollution research international · 2020Article
- Community-based burden, warning signs, and risk factors of cancer using public-private partnership model in Kerala, India.Journal of family medicine and primary care · 2020Article
- Occupational Risk Factors for Prostate Cancer: A Meta-analysis.Journal of cancer prevention · 2019Review
- Occupational exposure to pesticides: development of a job-exposure matrix for use in population-based studies (PESTIPOP).Journal of exposure science & environmental epidemiology · 2018Article
- Dioxin Exposure in the Manufacture of Pesticide Production as a Risk Factor for Death from Prostate Cancer: A Meta-analysis.Iranian journal of public health · 2018Review
- Risk of early-onset prostate cancer associated with occupation in the Nordic countries.European journal of cancer (Oxford, England : 1990) · 2017Article
- Cancer incidence in the AGRICAN cohort study (2005-2011).Cancer epidemiology · 2017Article
- Use of job-exposure matrices to estimate occupational exposure to pesticides: A review.Journal of exposure science & environmental epidemiology · 2017Review
- Toxicological profile of chlorophenols and their derivatives in the environment: the public health perspective.TheScientificWorldJournal · 2013Review
- Occupational pesticide exposures and cancer risk: a review.Journal of toxicology and environmental health. Part B, Critical reviews · 2012Review
- Prostate cancer and ambient pesticide exposure in agriculturally intensive areas in California.American journal of epidemiology · 2011Article
- [Non dietetic environmental risk factors in prostate cancer].Actas urologicas espanolas · 2011Article
- Plasma organochlorines and subsequent risk of prostate cancer in Japanese men: a nested case-control study.Environmental health perspectives · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo summarise recent literature on the risk of prostate cancer in pesticide related occupations, to calculate the meta-rate ratio, and to compare it to data from meta-analyses previously published.
methodsA meta-analysis of 22 epidemiological studies, published between 1995 and 2001, was conducted in order to pool their rate ratio estimates. Studies were summarised and evaluated for homogeneity and publication bias.
resultsThe meta-rate ratio estimate, based on 25 estimators of relative risk from 22 studies, was 1.13 (95% CI 1.04 to 1.22). Significant heterogeneity of rate ratios existed among the different studies. Therefore, a stratified analysis was carried out. Major sources of heterogeneity identified were geographic location, study design, and healthy worker effect. Overall, pooled risk estimates for studies derived from Europe were lower than those derived from the USA/Canada. A significant increase in rate ratio was observed for the occupation category of pesticide applicators, whereas no significant increase was observed for farmers. There was no evidence of publication bias.
conclusionThis increased meta-rate ratio for prostate cancer in different pesticide related occupations, including farmers, is very similar to three, previously published, meta-rate ratios for prostate cancer in farmers calculated from studies published before 1995. Although the underlying data do not identify pesticide exposure as an independent cause for prostate cancer, the fact that an increased meta-rate ratio is again obtained points to occupational exposure to pesticides as a possible factor. Future epidemiological studies should focus, as far as possible, on reliable methods to estimate actual exposure.
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