ArticleArchives of disease in childhood2003
Performance, treatment pathways, and effects of alternative policy options for screening for developmental dysplasia of the hip in the United Kingdom.
Article in Archives of disease in childhood, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Ultrasonography in screening for developmental dysplasia of the hip in newborns: systematic review.BMJ (Clinical research ed.) · 2005Pooled it
- DNA hypermethylation of GDF5 in developmental dysplasia of the hip (DDH).Molecular genetics & genomic medicine · 2019Trial
- Screening of Newborns and Infants for Developmental Dysplasia of the Hip: A Systematic Review.Indian journal of orthopaedics · 2021Review
- Effects of developmental dysplasia of the hip screening program on the treatment strategies: A retrospective study from a tertiary care hospital in the southeast region of Turkey.Acta orthopaedica et traumatologica turcica · 2021Article
- Implementation of a nationwide universal ultrasound screening programme for developmental dysplasia of the neonatal hip in Mongolia.Journal of children's orthopaedics · 2020Article
- Selective ultrasound screening for developmental hip dysplasia: effect on management and late detected cases. A prospective survey during 1991-2006.Pediatric radiology · 2014Article
- Bilateral One-half Spica Cast After Open Reduction and Pelvic Osteotomy in the Developmental Dislocation of the Hip.Iranian Red Crescent medical journal · 2013Article
- Ultrasonography in developmental dysplasia of the hip: what have we learned?Pediatric radiology · 2012Review
- Screening for developmental dysplasia of the hip: current practices in Ireland.Irish journal of medical science · 2010Article
- [When is the optimal time for hip ultrasound screening?].Der Orthopade · 2008Article
- [Hip ultrasound screening in Germany. Results and comparison with other screening procedures].Der Orthopade · 2008Article
- Associated risk factors in children who had late presentation of developmental dysplasia of the hip.Journal of children's orthopaedics · 2007Article
- Differences in risk factors between early and late diagnosed developmental dysplasia of the hip.Archives of disease in childhood. Fetal and neonatal edition · 2006Article
- Hip dysplasia and ultrasound imaging of whole populations: the precautionary principle revisited.Archives of disease in childhood. Fetal and neonatal edition · 2005Article
- Etamsylate for prevention of periventricular haemorrhage.Archives of disease in childhood. Fetal and neonatal edition · 2005Article
- Efficiency of alternative policy options for screening for developmental dysplasia of the hip in the United Kingdom.Archives of disease in childhood · 2003Article
- Developmental dysplasia of the hip in infants referred for a combined pediatric orthopedic and radiologic examination. A prospective cohort study.Journal of orthopaedicsArticle
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo compare, using a decision model, performance, treatment pathways and effects of different newborn screening strategies for developmental hip dysplasia with no screening.
methodsDetection rate, radiological absence of subluxation at skeletal maturity and avascular necrosis of the femoral head, as favourable and unfavourable treatment outcomes respectively, were compared for the following strategies: clinical screening alone using the Ortolani and Barlow tests; the addition of static and dynamic ultrasound examination of the hips of all infants (universal ultrasound) or restricted to infants with defined risk factors (selective ultrasound); "no screening" (that is, clinical diagnosis only).
resultsUniversal or selective ultrasound detects more more affected children (76% and 60% respectively) than clinical screening alone (35%), results in a higher proportion of affected children with favourable treatment outcomes (92% and 88% respectively) than clinical screening alone (78%) or no screening (75%), and the highest proportion of these achieved without recourse to surgery (64% and 79% respectively) compared with clinical screening alone (18%). However, ultrasound based strategies are also associated with the highest number of unfavourable treatment outcomes arising in unaffected children treated following a false positive screening result. The detection rate of clinical screening alone becomes similar to that reported for universal ultrasound when based on studies using experienced examiners (80%) rather than junior medical staff (35%).
conclusionFrom the largely observational data available, ultrasound based screening strategies appear to be most sensitive and effective but are associated with the greatest risk of potential adverse iatrogenic effects arising in unaffected children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.