Evidence map›Paper›PMID 12937019›Full record

ArticleAntimicrobial agents and chemotherapy2003

Real-time PCR as a versatile tool for investigating the susceptibility of human herpesvirus 6 to antiviral agents.

Muriel Macé, Chaysavanh Manichanh, Pascale Bonnafous, Stéphanie Précigout, David Boutolleau, Agnès Gautheret-Dejean, Henri Agut

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Muriel MacéLaboratoire de Virologie, UPRES EA2387, CERVI, Groupe Hospitalier Pitié-Salpêtrière, 75013 Paris, France.
Chaysavanh Manichanh
Pascale Bonnafous
Stéphanie Précigout
David Boutolleau
Agnès Gautheret-Dejean
Henri Agut

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A quantitative real-time PCR assay was developed for the determination of antiviral drug susceptibility and growth kinetics of human herpesvirus 6. The susceptibility and fitness of a sensitive strain, HST, and its ganciclovir-resistant derivative, GCVR1, were then characterized, leading us to conclude that the mutations of this latter virus did not alter its fitness significantly.

Indexed as

Antiviral AgentsCells, CulturedDNA, ViralFlow CytometryHerpesvirus 6, HumanHumansMicrobial Sensitivity TestsReverse Transcriptase Polymerase Chain ReactionVirus ReplicationAntiviral AgentsDNA, Viral

Identifiers

PMID12937019
PMCPMC182648

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.