ArticleInfection and immunity2003
Nicotinamide ribosyl uptake mutants in Haemophilus influenzae.
Article in Infection and immunity, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Phage-encoded NARP3 system rebuilds NADScience advances · 2026Article
- cAMP competitively inhibits periplasmic phosphatases to coordinate nutritional growth with competence of Haemophilus influenzae.The Journal of biological chemistry · 2023Article
- Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans.npj aging · 2023Article
- The CD38 glycohydrolase and the NAD sink: implications for pathological conditions.American journal of physiology. Cell physiology · 2022Review
- Regulation of NADMetabolism: clinical and experimental · 2022Review
- A second riboswitch class for the enzyme cofactor NADRNA (New York, N.Y.) · 2021Article
- The Multi-faceted Ecto-enzyme CD38: Roles in Immunomodulation, Cancer, Aging, and Metabolic Diseases.Frontiers in immunology · 2019Review
- Niacin-mediated Gene Expression and Role of NiaR as a Transcriptional Repressor ofFrontiers in cellular and infection microbiology · 2017Article
- Functional mining of transporters using synthetic selections.Nature chemical biology · 2016Article
- Characterization of NAD salvage pathways and their role in virulence in Streptococcus pneumoniae.Microbiology (Reading, England) · 2015Article
- NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus.Cell metabolism · 2015Review
- Crystal structure of the vitamin B3 transporter PnuC, a full-length SWEET homolog.Nature structural & molecular biology · 2014Article
- Evolution of the oligopeptide transporter family.The Journal of membrane biology · 2011Article
- NAD+ utilization in Pasteurellaceae: simplification of a complex pathway.Journal of bacteriology · 2006Review
- Coupling of NAD+ biosynthesis and nicotinamide ribosyl transport: characterization of NadR ribonucleotide kinase mutants of Haemophilus influenzae.Journal of bacteriology · 2005Article
- PnuC and the utilization of the nicotinamide riboside analog 3-aminopyridine in Haemophilus influenzae.Antimicrobial agents and chemotherapy · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gene for the nicotinamide riboside (NR) transporter (pnuC) was identified in Haemophilus influenzae. A pnuC mutant had only residual NR uptake and could survive in vitro with high concentrations of NR, but could not survive in vivo. PnuC may represent a target for the development of inhibitors for preventing H. influenzae disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.