ArticleInfection and immunity2003
Intracellular survival of Streptococcus pyogenes in polymorphonuclear cells results in increased bacterial virulence.
Article in Infection and immunity, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 77 citations in OpenAlex.
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- Inflammatory Response Genes' Polymorphism Associated with Risk of Rheumatic Heart Disease.Journal of personalized medicine · 2024Article
- The tellurite resistance gene cluster of pathogenic bacteria and its effect on oxidative stress response.Folia microbiologica · 2024Article
- Synthetic mRNA delivered to human cells leads to expression of Cpl-1 bacteriophage-endolysin with activity againstMolecular therapy. Nucleic acids · 2024Article
- StreptococcusVirulence · 2023Article
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- Nano-Based Drug Delivery or Targeting to Eradicate Bacteria for Infection Mitigation: A Review of Recent Advances.Frontiers in chemistry · 2020Review
- Intracellular Invasion byMicrobiology spectrum · 2019Review
- Intracellular Streptococcal Uptake and Persistence: A Potential Cause of Erysipelas Recurrence.Frontiers in medicine · 2019Article
- Cytotoxicity and Survival Fitness of InvasiveFrontiers in microbiology · 2018Article
- Group A Streptococcus encounters with host macrophages.Future microbiology · 2018Review
- New insights into valve-related intramural and intracellular bacterial diversity in infective endocarditis.PloS one · 2017Article
- Article
- IL-1α-induced microvascular endothelial cells promote neutrophil killing by increasing MMP-9 concentration and lysozyme activity.Immunologic research · 2016Article
- Microbiology of peritonsillar abscess in the South Estonian population.Microbial ecology in health and disease · 2016Article
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- Article
- Article
- The M1 protein of Streptococcus pyogenes triggers an innate uptake mechanism into polarized human endothelial cells.Journal of innate immunity · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has recently been shown that survival within phagocytic cells constitutes an additional strategy used by Streptococcus pyogenes to evade the host defenses. Here we provide evidence that S. pyogenes can escape from the phagosome into the cytoplasm of phagocytic cells. Furthermore, intracellular bacteria seem to undergo phenotypic switching that results in much more virulent microorganisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.