ArticleNucleic acids research2003
Parallel gene analysis with allele-specific padlock probes and tag microarrays.
Article in Nucleic acids research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 115 citations in OpenAlex.
- 10 × Genomics Flex Gene Expression is a powerful tool for single-cell transcriptomics of xenografts models.Genome biology · 2026Article
- Ultra-sensitive monitoring of leukemia patients using superRCA mutation detection assays.Nature communications · 2022Article
- PaintSHOP enables the interactive design of transcriptome- and genome-scale oligonucleotide FISH experiments.Nature methods · 2021Article
- OligoMiner provides a rapid, flexible environment for the design of genome-scale oligonucleotide in situ hybridization probes.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Fidelity of RNA templated end-joining by chlorella virus DNA ligase and a novel iLock assay with improved direct RNA detection accuracy.Nucleic acids research · 2017Article
- Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnostics.International journal of molecular sciences · 2014Review
- Comparison and transfer testing of multiplex ligation detection methods for GM plants.BMC biotechnology · 2012Article
- Multiplex cDNA quantification method that facilitates the standardization of gene expression data.Nucleic acids research · 2011Article
- Multiplexed genotyping of methicillin-resistant Staphylococcus aureus isolates by use of padlock probes and tag microarrays.Journal of clinical microbiology · 2009Article
- A single molecule array for digital targeted molecular analyses.Nucleic acids research · 2009Article
- Simultaneous genotyping of all hemagglutinin and neuraminidase subtypes of avian influenza viruses by use of padlock probes.Journal of clinical microbiology · 2008Article
- A dual-tag microarray platform for high-performance nucleic acid and protein analyses.Nucleic acids research · 2008Article
- Duality of polynucleotide substrates for Phi29 DNA polymerase: 3'-->5' RNase activity of the enzyme.RNA (New York, N.Y.) · 2008Article
- Quantitative multiplex detection of plant pathogens using a novel ligation probe-based system coupled with universal, high-throughput real-time PCR on OpenArrays.BMC genomics · 2007Article
- Review
- Unravelling microbial communities with DNA-microarrays: challenges and future directions.Microbial ecology · 2007Review
- Article
- Lock and roll: single-molecule genotyping in situ using padlock probes and rolling-circle amplification.Histochemistry and cell biology · 2006Review
- ProbeMaker: an extensible framework for design of sets of oligonucleotide probes.BMC bioinformatics · 2005Article
- Multiplex amplification enabled by selective circularization of large sets of genomic DNA fragments.Nucleic acids research · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parallel, highly specific analysis methods are required to take advantage of the extensive information about DNA sequence variation and of expressed sequences. We present a scalable laboratory technique suitable to analyze numerous target sequences in multiplexed assays. Sets of padlock probes were applied to analyze single nucleotide variation directly in total genomic DNA or cDNA for parallel genotyping or gene expression analysis. All reacted probes were then co-amplified and identified by hybridization to a standard tag oligonucleotide array. The technique was illustrated by analyzing normal and pathogenic variation within the Wilson disease-related ATP7B gene, both at the level of DNA and RNA, using allele-specific padlock probes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.