Evidence map›Paper›PMID 12925889›Full record

ArticleMammalian genome : official journal of the International Mammalian Genome Society2003

EST-based gene discovery in pig: virtual expression patterns and comparative mapping to human.

Christopher K Tuggle, Jon A Green, Carolyn Fitzsimmons, Rami Woods, Randall S Prather, Sergei Malchenko, Bento M Soares, Tamara Kucaba, Keith Crouch, Christina Smith and 11 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 57 citations in OpenAlex.

  1. Genome-wide profiling of Sus scrofa circular RNAs across nine organs and three developmental stages.DNA research : an international journal for rapid publication of reports on genes and genomes · 2017
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Novel Gene Discovery in the Human Malaria Parasite using Nucleosome Positioning Data.Computational systems bioinformatics. Computational Systems Bioinformatics Conference · 2010
    Article
  7. Article
  8. Article
  9. Advances in swine transcriptomics.International journal of biological sciences · 2007
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. EST-based analysis of gene expression in the porcine brain.Genomics, proteomics & bioinformatics · 2004
    Article
  15. High-resolution comparative mapping of pig Chromosome 4, emphasizing the FAT1 region.Mammalian genome : official journal of the International Mammalian Genome Society · 2004
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 5 institutions in 1 country.

Christopher K TuggleCenter for Integrated Animal Genomics and Department of Animal Science, Iowa State University, 2255 Kildee Hall, Ames, Iowa 50011, USA. cktuggle@iastate.edu
Jon A Green
Carolyn Fitzsimmons
Rami Woods
Randall S Prather
Sergei Malchenko
Bento M Soares
Tamara Kucaba
Keith Crouch
Christina Smith
Dylan Tack
Natalie Robinson
Brian O'Leary
Todd Scheetz
Thomas Casavant
Daniel Pomp
Brad J Edeal
Yuandan Zhang
Max F Rothschild
Kevin Garwood
William Beavis
University of Iowa · USIowa State University · USUniversity of Missouri · USNational Center for Genome Resources · USUniversity of Nebraska–Lincoln · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A molecular understanding of porcine reproduction is of biological interest and economic importance. Our Midwest Consortium has produced cDNA libraries containing the majority of genes expressed in major female reproductive tissues, and we have deposited into public databases 21,499 expressed sequence tag (EST) gene sequences from the 3' end of clones from these libraries. These sequences represent 10,574 different genes, based on sequence comparison among these data, and comparison with existing porcine ESTs and genes indicate as many as 4652 of these EST clusters are novel. In silico analysis identified sequences that are expressed in specific pig tissues or organs and confirmed the broad expression in pig for many genes ubiquitously expressed in human tissues. Furthermore, we have developed computer software to identify sequence similarity of these pig genes with their human counterparts, and to extract the mapping information of these human homologues from genome databases. We demonstrate the utility of this software for comparative mapping by localizing 61 genes on the porcine physical map for Chromosomes (Chrs) 5, 10, and 14.

Indexed as

Chromosome MappingExpressed Sequence TagsGene ExpressionGene LibraryAlgorithmsAnimalsBase SequenceHumansHybrid CellsMolecular Sequence DataSequence Analysis, DNASus scrofa

Identifiers

PMID12925889
OpenAlexW2049217322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.