Evidence map›Paper›PMID 12925426›Full record

ReviewCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2003

Diagnosis and management of anaphylaxis.

Anne K Ellis, James H Day

Open access · greenAbstract readCase ReportsReview
In one paragraph

Review in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 154 citations in OpenAlex.

  1. Anaphylaxis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
    Review
  2. Article
  3. Article
  4. Article
  5. A Case Report of Prolonged Anaphylaxis after COVID-19 Vaccine.Clinical practice and cases in emergency medicine · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Anaphylaxis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2018
    Review
  10. Outpatient Emergencies: Anaphylaxis.The Medical clinics of North America · 2017
    Review
  11. Adverse events related to blood transfusion.Indian journal of anaesthesia · 2014
    Review
  12. Acute treatment of anaphylaxis in children.Canadian family physician Medecin de famille canadien · 2013
    Article
  13. Fish-oil capsule ingestion: a case of recurrent anaphylaxis.Canadian family physician Medecin de famille canadien · 2012
    Article
  14. Anaphylaxis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2011
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Navigating the updated anaphylaxis parameters.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2007
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Anne K EllisDepartment of Medicine, Queen's University, and the Division of Allergy and Immunology, Kingston General Hospital, Kingston, ON. ellisa@kgh.kari.net
James H Day
Queen's University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anaphylaxis is a severe systemic allergic reaction that is potentially fatal. It requires prompt recognition and immediate management. Anaphylaxis has a rapid onset with multiple organ-system involvement and is mostly caused by specific antigens in sensitized individuals. Reactions typically follow a uniphasic course, however, 20% will be biphasic in nature. The second phase usually occurs after an asymptomatic period of 1-8 hours, but there may be a 24-hour delay. Protracted anaphylaxis may persist beyond 24 hours. Concurrent beta-blocker therapy may adversely affect the response to management. Epinephrine is the treatment of choice and should be administered immediately. Secondary measures include circulatory support, H(1) and H(2) antagonists, corticosteroids and, occasionally, bronchodilators. Post-treatment observation of these patients is necessary, and they should remain within ready access of emergency care for the following 48 hours.

Indexed as

AdultAnaphylaxisAnti-Allergic AgentsFemaleHumansImmunotherapyAnti-Allergic Agents

Identifiers

PMID12925426
PMCPMC180656
OpenAlexW2140082814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.