ArticleProceedings of the National Academy of Sciences of the United States of America2003
Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 185 papers.
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185 citing papers in PubMed, 468 citations in OpenAlex.
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- Heterologous expression in E. coli reveals that bicarbonate transporter BicA2 mediates carbon uptake in marine Prochlorococcus spp.The ISME journal · 2026Article
- Picocyanobacteria in the Chesapeake Bay: isolation, diversity, and adaptation.Marine life science & technology · 2025Review
- Adaptive Evolution Signatures inMicroorganisms · 2024Article
- Protein NirP1 regulates nitrite reductase and nitrite excretion in cyanobacteria.Nature communications · 2024Article
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- Introduction to Cyanobacteria.Advances in biochemical engineering/biotechnology · 2023Article
- Elucidating the picocyanobacteria salinity divide through ecogenomics of new freshwater isolates.BMC biology · 2022Article
- Priorities for ocean microbiome research.Nature microbiology · 2022Review
- Exploring the Diversity of the Thioredoxin Systems in Cyanobacteria.Antioxidants (Basel, Switzerland) · 2022Review
- Novel functional insights into a modified sugar-binding protein from Synechococcus MITS9220.Scientific reports · 2022Article
- Functional characterisation of substrate-binding proteins to address nutrient uptake in marine picocyanobacteria.Biochemical Society transactions · 2021Review
- Size-Fractionated Filtration Combined with Molecular Methods Reveals the Size and Diversity of Picophytoplankton.Biology · 2021Article
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- Bioactive Metabolites Produced by Cyanobacteria for Growth Adaptation and Their Pharmacological Properties.Biology · 2021Review
- Review
125 more citing papers are in PubMed but not listed here.
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21 authors at 1 institution in 1 country.
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Abstract
Prochlorococcus marinus, the dominant photosynthetic organism in the ocean, is found in two main ecological forms: high-light-adapted genotypes in the upper part of the water column and low-light-adapted genotypes at the bottom of the illuminated layer. P. marinus SS120, the complete genome sequence reported here, is an extremely low-light-adapted form. The genome of P. marinus SS120 is composed of a single circular chromosome of 1,751,080 bp with an average G+C content of 36.4%. It contains 1,884 predicted protein-coding genes with an average size of 825 bp, a single rRNA operon, and 40 tRNA genes. Together with the 1.66-Mbp genome of P. marinus MED4, the genome of P. marinus SS120 is one of the two smallest genomes of a photosynthetic organism known to date. It lacks many genes that are involved in photosynthesis, DNA repair, solute uptake, intermediary metabolism, motility, phototaxis, and other functions that are conserved among other cyanobacteria. Systems of signal transduction and environmental stress response show a particularly drastic reduction in the number of components, even taking into account the small size of the SS120 genome. In contrast, housekeeping genes, which encode enzymes of amino acid, nucleotide, cofactor, and cell wall biosynthesis, are all present. Because of its remarkable compactness, the genome of P. marinus SS120 might approximate the minimal gene complement of a photosynthetic organism.
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