ArticleJournal of biomolecular NMR2003
Rotational diffusion tensor of nucleic acids from 13C NMR relaxation.
Article in Journal of biomolecular NMR, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- N-terminal domain of polypyrimidine-tract binding protein is a dynamic folding platform for adaptive RNA recognition.Nucleic acids research · 2024Article
- Base Dynamics in theThe journal of physical chemistry. B · 2023Article
- DNA base order parameter determination without influence of chemical exchange.Methods (San Diego, Calif.) · 2023Article
- Isotope Labels Combined with Solution NMR Spectroscopy Make Visible the Invisible Conformations of Small-to-Large RNAs.Chemical reviews · 2022Review
- Deleterious effects of carbon-carbon dipolar coupling on RNA NMR dynamics.Journal of biomolecular NMR · 2020Article
- Resolving sugar puckers in RNA excited states exposes slow modes of repuckering dynamics.Nucleic acids research · 2017Article
- Chemo-enzymatic synthesis of site-specific isotopically labeled nucleotides for use in NMR resonance assignment, dynamics and structural characterizations.Nucleic acids research · 2016Article
- Rapid Exchange Between Free and Bound States in RNA-Dendrimer Polyplexes: Implications on the Mechanism of Delivery and Release.Biomacromolecules · 2016Article
- Structural fidelity and NMR relaxation analysis in a prototype RNA hairpin.RNA (New York, N.Y.) · 2015Article
- Deriving quantitative dynamics information for proteins and RNAs using ROTDIF with a graphical user interface.Journal of biomolecular NMR · 2013Article
- Intrinsic nucleic acid dynamics modulates HIV-1 nucleocapsid protein binding to its targets.PloS one · 2012Article
- Asymmetry of 13C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy.Journal of biomolecular NMR · 2012Article
- Asymmetry of (13)C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy.Journal of biomolecular NMR · 2011Article
- Characterizing RNA dynamics at atomic resolution using solution-state NMR spectroscopy.Nature methods · 2011Review
- Selective 13C labeling of nucleotides for large RNA NMR spectroscopy using an E. coli strain disabled in the TCA cycle.Journal of biomolecular NMR · 2010Article
- Extensive backbone dynamics in the GCAA RNA tetraloop analyzed using 13C NMR spin relaxation and specific isotope labeling.Journal of the American Chemical Society · 2008Article
- Furanose dynamics in the HhaI methyltransferase target DNA studied by solution and solid-state NMR relaxation.The journal of physical chemistry. B · 2008Article
- Cytosine ribose flexibility in DNA: a combined NMR 13C spin relaxation and molecular dynamics simulation study.Nucleic acids research · 2008Article
- NMR and MD studies of the temperature-dependent dynamics of RNA YNMG-tetraloops.Nucleic acids research · 2008Article
- Conserved nucleotides in an RNA essential for hepatitis B virus replication show distinct mobility patterns.Nucleic acids research · 2007Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Rotational diffusion properties have been derived for the DNA dodecamer d(CGCGAATTCGCG)(2) from (13)C R(1rho) and R(1) measurements on the C(1'), C(3'), and C(4') carbons in samples uniformly enriched in (13)C. The narrow range of C-H bond vector orientations relative to the DNA axis make the analysis particularly sensitive to small structural deviations. As a result, the R(1rho)/R(1) ratios are found to fit poorly to the crystal structures of this dodecamer, but well to a recent solution NMR structure, determined in liquid crystalline media, even though globally the structures are quite similar. A fit of the R(1rho)/R(1) ratios to the solution structure is optimal for an axially symmetric rotational diffusion model, with a diffusion anisotropy, D(\|)/D(perpendicular), of 2.1+/-0.4, and an overall rotational correlation time, (2D(\|)+4D(perpendicular))(-1), of 3.35 ns at 35 degrees C in D(2)O, in excellent agreement with values obtained from hydrodynamic modeling.
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