ArticlePlant physiology2003
Expression profiling of cytokinin action in Arabidopsis.
Article in Plant physiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
131 citing papers in PubMed, 1 synthesis or guideline pooled it, 311 citations in OpenAlex.
- Identification of cytokinin-responsive genes using microarray meta-analysis and RNA-Seq in Arabidopsis.Plant physiology · 2013Pooled it
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- Growth regulation during early fruit development in apple (Malus × domestica Borkh.): a temporal event map of transcriptome and phytohormone changes.BMC plant biology · 2025Article
- Identification of a natural RcLOG1 allele linked to prickle development in Rose (Rosa spp.).Planta · 2025Article
- Non-Canonical Inter-Protein Interactions of Key Proteins Belonging to Cytokinin Signaling Pathways.Plants (Basel, Switzerland) · 2025Review
- Transcriptional Dynamics Underlying Somatic Embryogenesis inPlants (Basel, Switzerland) · 2025Article
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- Genome-wide association study and selective sweep analysis uncover candidate genes controlling curd branch length in cauliflower.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- The structure of B-ARR reveals the molecular basis of transcriptional activation by cytokinin.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genome-wide analysis of radishFrontiers in plant science · 2024Article
- Cloning and Functional Analysis of thePlants (Basel, Switzerland) · 2023Article
- Gain-of-function of the cytokinin response activator ARR1 increases heat shock tolerance inPlant signaling & behavior · 2022Article
- Overexpression of AHL9 accelerates leaf senescence in Arabidopsis thaliana.BMC plant biology · 2022Article
- Biotechnological Advances in Pharmacognosy and In Vitro Manipulation ofPlants (Basel, Switzerland) · 2022Review
- Genetic and molecular pathways controlling rice inflorescence architecture.Frontiers in plant science · 2022Review
- ABCG11 modulates cytokinin responses inFrontiers in plant science · 2022Article
- Diverse Effect of Two Cytokinins, Kinetin and Benzyladenine, on Plant Development, Biotic Stress Tolerance, and Gene Expression.Life (Basel, Switzerland) · 2021Article
71 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The phytohormone cytokinin is an important regulator of plant growth and development; however, relatively few genes that mediate cytokinin responses have been identified. Genome-wide analyses of Arabidopsis seedlings using the approximately 8,300-element Affymetrix Arabidopsis GeneChips (Affymetrix, Santa Clara, CA) to examine cytokinin-responsive genes were conducted, revealing at least 30 genes whose steady-state level of mRNA was elevated and at least 40 that were down-regulated at multiple time points after application of cytokinin. The cytokinin up-regulated genes include the type-A Arabidopsis response regulators (ARRs), which had been shown previously to be cytokinin primary response genes, cytokinin oxidase, which encodes an enzyme that degrades cytokinins, and several transcription factors. Cytokinin down-regulated genes include several peroxidases and kinases and an E3 ubiquitin ligase. We identified a common sequence motif enriched in the upstream regions of the most consistently cytokinin up-regulated genes. This motif is highly similar to the optimal DNA-binding sites for ARR1/ARR2, type-B ARRs that have been implicated in the transcriptional elevation of the type-A ARRs. Additionally, genome-wide analyses of cytokinin receptor mutants (wol/cre1) revealed large-scale changes in gene expression, including down-regulation of the type-A ARRs and several meristem and cell cycle genes, such as CycD3. Mutations in CRE1 reduced but did not eliminate the effect of cytokinin on gene expression for a subset of cytokinin-responsive genes and had little or no effect on others, suggesting functional redundancy among the cytokinin receptors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.