Evidence map›Paper›PMID 12912901›Full record

ArticleEukaryotic cell2003

Specific protein targeting during cell differentiation: polarized localization of Fus1p during mating depends on Chs5p in Saccharomyces cerevisiae.

Beatriz Santos, Michael Snyder

Abstract read
In one paragraph

Article in Eukaryotic cell, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Conventional and Unconventional Protein Secretion in Yeast and Animal Cells.Methods in molecular biology (Clifton, N.J.) · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. The exomer cargo adaptor features a flexible hinge domain.Structure (London, England : 1993) · 2013
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast.Proceedings of the National Academy of Sciences of the United States of America · 2005
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Beatriz SantosMolecular, Cellular, and Developmental Biology Department, Yale University, New Haven, Connecticut 06520-8103, USA.
Michael Snyder

Funding

TWO SIGNALING PATHWAYS INVOLVED IN YEAST MORPHOGENESISR01GM036494 · NIGMS · YALE UNIVERSITY · PI SNYDER, MICHAEL P · 1986 to 2007
$2.7M
NIGMS NIH HHS GM36494NIGMS NIH HHS R01 GM036494
6 · The paper itself

Abstract

In budding yeast, chs5 mutants are defective in chitin synthesis and cell fusion during mating. Chs5p is a late-Golgi protein required for the polarized transport of the chitin synthase Chs3p to the membrane. Here we show that Chs5p is also essential for the polarized targeting of Fus1p, but not of other cell fusion proteins, to the membrane during mating.

Indexed as

Saccharomyces cerevisiae ProteinsCell CompartmentationCell DifferentiationCell MembraneCell PolarityCells, CulturedChitinChitin SynthaseFungal ProteinsMembrane FusionMembrane ProteinsMutationProtein TransportRecombinant Fusion ProteinsReproductionSaccharomyces cerevisiaeChitinChitin SynthaseCHS5 protein, S cerevisiaeFungal ProteinsFUS1 protein, S cerevisiaeMembrane ProteinsRecombinant Fusion ProteinsSaccharomyces cerevisiae Proteins

Identifiers

PMID12912901
PMCPMC178347

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.