ArticleChromosoma1992
Control of DNA synthesis genes in budding yeast: involvement of the transcriptional modulator MOT1 in the expression of the DNA polymerase alpha gene.
Article in Chromosoma, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
- The Modifier of Transcription 1 (Mot1) ATPase and Spt16 Histone Chaperone Co-regulate Transcription through Preinitiation Complex Assembly and Nucleosome Organization.The Journal of biological chemistry · 2016Article
- One small step for Mot1; one giant leap for other Swi2/Snf2 enzymes?Biochimica et biophysica acta · 2011Review
- Genetic analysis connects SLX5 and SLX8 to the SUMO pathway in Saccharomyces cerevisiae.Genetics · 2006Article
- Differential requirement of SAGA subunits for Mot1p and Taf1p recruitment in gene activation.Molecular and cellular biology · 2005Article
- Mot1 activates and represses transcription by direct, ATPase-dependent mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- MOT1-catalyzed TBP-DNA disruption: uncoupling DNA conformational change and role of upstream DNA.The EMBO journal · 2001Article
- The gene for human TATA-binding-protein-associated factor (TAFII) 170: structure, promoter and chromosomal localization.The Biochemical journal · 2000Article
- MOT1 can activate basal transcription in vitro by regulating the distribution of TATA binding protein between promoter and nonpromoter sites.Molecular and cellular biology · 1999Article
- Molecular genetics of the RNA polymerase II general transcriptional machinery.Microbiology and molecular biology reviews : MMBR · 1998Review
- Identification and analysis of Mot3, a zinc finger protein that binds to the retrotransposon Ty long terminal repeat (delta) in Saccharomyces cerevisiae.Molecular and cellular biology · 1998Article
- Cloning and biochemical characterization of TAF-172, a human homolog of yeast Mot1.Molecular and cellular biology · 1998Article
- Cloning of the cDNA for the TATA-binding protein-associated factorII170 subunit of transcription factor B-TFIID reveals homology to global transcription regulators in yeast and Drosophila.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- Molecular analysis of the SNF2/SWI2 protein family member MOT1, an ATP-driven enzyme that dissociates TATA-binding protein from DNA.Molecular and cellular biology · 1997Article
- Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2 in vivo.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- Expanding the Mot1 subfamily: 89B helicase encodes a new Drosophila melanogaster SNF2-related protein which binds to multiple sites on polytene chromosomes.Nucleic acids research · 1996Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodic transcription during the cell cycle of the budding yeast DNA polymerase alpha gene (POL1) requires the cis-acting element 5' ACGCGT 3', which has been found in the 5' non-coding region of all the DNA synthesis genes analyzed so far. Search for trans-acting mutations affecting POL1 expression led to the isolation of the temperature-sensitive reg1033 mutant, that showed increased levels of both DNA polymerase alpha and delta gene transcripts. Cloning of the REG1033 gene demonstrated that it is essential for cell viability and required for proper expression of the POL1 gene. DNA sequence comparison established that the REG1033 gene is identical to MOT1, a gene encoding a presumptive DNA helicase which modulates transcription of several yeast genes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.