ArticleHistochemistry and cell biology2003
Interrelations between monoaminergic afferents and corticotropin-releasing factor-immunoreactive neurons in the rat central amygdaloid nucleus: ultrastructural evidence for dopaminergic control of amygdaloid stress systems.
Article in Histochemistry and cell biology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Impact of serotonin transporter deficiency on parvalbumin- and neuropeptide Y-producing neurons of the lateral and basolateral amygdalar nuclei.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Synaptic Effects Induced by Alcohol.Current topics in behavioral neurosciences · 2025Review
- Reciprocal midbrain-extended amygdala circuit activity in preclinical models of alcohol use and misuse.Neuropharmacology · 2022Review
- Mesolimbic neuropeptide W coordinates stress responses under novel environments.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Effect of dopamine D1 and D2 receptor antagonism in the lateral hypothalamus on the expression and acquisition of fructose-conditioned flavor preference in rats.Brain research · 2014Article
- Corticotropin releasing factor and catecholamines enhance glutamatergic neurotransmission in the lateral subdivision of the central amygdala.Neuropharmacology · 2013Article
- Serotonergic innervation of the amygdala: targets, receptors, and implications for stress and anxiety.Histochemistry and cell biology · 2013Review
- Serotonergic innervation and serotonin receptor expression of NPY-producing neurons in the rat lateral and basolateral amygdaloid nuclei.Brain structure & function · 2013Article
- GABA concentration and GABAergic neuron populations in limbic areas are differentially altered by brain serotonin deficiency in Tph2 knockout mice.Histochemistry and cell biology · 2013Article
- Synaptic effects induced by alcohol.Current topics in behavioral neurosciences · 2013Review
- Allostasis and addiction: role of the dopamine and corticotropin-releasing factor systems.Physiology & behavior · 2012Review
- Double and triple in situ hybridization for coexpression studies: combined fluorescent and chromogenic detection of neuropeptide Y (NPY) and serotonin receptor subtype mRNAs expressed at different abundance levels.Histochemistry and cell biology · 2012Article
- Unraveling glutamate-opioid receptor interactions using high-resolution electron microscopy: implications for addiction-related processes.Experimental neurology · 2011Article
- Dopamine receptor mechanisms mediate corticotropin-releasing factor-induced long-term potentiation in the rat amygdala following cocaine withdrawal.The European journal of neuroscience · 2010Article
- Role of amygdala dopamine D1 and D2 receptors in the acquisition and expression of fructose-conditioned flavor preferences in rats.Behavioural brain research · 2009Article
- Interaction between noradrenaline and corticotrophin-releasing factor in the reinstatement of cocaine seeking in the rat.Psychopharmacology · 2009Article
- Presynaptic CRF1 receptors mediate the ethanol enhancement of GABAergic transmission in the mouse central amygdala.TheScientificWorldJournal · 2009Article
- Role of dopamine D1 and D2 receptors in CRF-induced disruption of sensorimotor gating.Pharmacology, biochemistry, and behavior · 2007Article
- Behavioral and anatomical interactions between dopamine and corticotropin-releasing factor in the rat.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
- Corticotropin-releasing factor receptors CRF1 and CRF2 exert both additive and opposing influences on defensive startle behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ample evidence implicates corticotropin-releasing factor (CRF)-producing neurons of the central amygdaloid nucleus (CeA) in vegetative, endocrine, and behavioral responses to stress and anxiety in laboratory rats. Monoaminergic systems are involved in modulating these responses. In the present paper, interrelations between CRF-immunoreactive (ir) neurons, and noradrenergic, serotonergic, and dopaminergic afferents were studied using single and double immunolabeling for light and electron microscopy in the rat CeA. Dopaminergic axons formed dense plexus in the CeA overlapping with the localization of CRF-ir neurons, and their terminals formed frequent associations with CRF-ir somata. Contacts of serotonergic axons on CRF-ir neurons were few, and contacts of noradrenergic axons were the exception. Ultrastructurally, symmetric synapses of dopaminergic terminals on CRF-ir somata and dendrites were found. More than 83% of CRF-ir somata were contacted in single ultrathin sections. About half of these possessed two or more contacts. Of non-ir somata, 37% were contacted by dopaminergic terminals, and only 13% of these had two or more contacts. Correlative in situ hybridization indicated that CeA CRF-ir neurons may express receptor subtype dopamine receptor subtype 2. In conclusion, dopaminergic afferents appear to specifically target CeA CRF neurons. They are thus in a position to exert significant influence on the rat amygdaloid CRF stress system.
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