ReviewOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2003
Osteoporosis after solid organ and bone marrow transplantation.
Review in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 193 citations in OpenAlex.
- Updated recommendations for the diagnosis and management of osteoporosis: a local perspective.Annals of Saudi medicineGuideline
- Zoledronic acid versus alendronate for the prevention of bone loss after heart or liver transplantation.The Journal of clinical endocrinology and metabolism · 2012Trial
- Skeletal findings in children recently initiating glucocorticoids for the treatment of nephrotic syndrome.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2012Trial
- Serum osteoprotegerin and receptor activator of nuclear factor-kappaB ligand (RANKL) concentrations in allogeneic stem cell transplant-recipients: a role in bone loss?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2006Trial
- Vertebral fracture incidence and risk factors following liver transplantation: tertiary transplant center experience.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Osteoporosis and Bone Fragility in Children: Diagnostic and Treatment Strategies.Journal of clinical medicine · 2024Review
- Physical Exercise After Solid Organ Transplantation: A Cautionary Tale.Transplant international : official journal of the European Society for Organ Transplantation · 2024Review
- High risk of osteoporosis and fracture following solid organ transplantation: a population-based study.Frontiers in endocrinology · 2023Article
- Timing of Osteoporotic Vertebral Fractures in Lung and Heart Transplantation: A Longitudinal Study.Journal of clinical medicine · 2020Article
- Effect of Bisphosphonates on Bone Health in Adult Renal Transplant Patients: Beyond the First Year Posttransplant-A Systematic Review and Meta-Analysis.Canadian journal of kidney health and disease · 2019Article
- Osteoporosis in Children with Chronic Illnesses: Diagnosis, Monitoring, and Treatment.Current osteoporosis reports · 2017Review
- Article
- Current Status of Research on Osteoporosis after Solid Organ Transplantation: Pathogenesis and Management.BioMed research international · 2015Review
- Short-term glucocorticoid treatment causes spinal osteoporosis in ovariectomized rats.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2014Article
- Incidence of fractures after cardiac and lung transplantation: a single center experience.Journal of osteoporosis · 2014Article
- Long-term linear growth and puberty in pediatric liver transplant recipients.The Journal of pediatrics · 2013Article
- [Secondary osteoporosis: pathogenesis, types, diagnostics and therapy].Der Radiologe · 2011Article
- Elevated incidence of fractures in solid-organ transplant recipients on glucocorticoid-sparing immunosuppressive regimens.Journal of osteoporosis · 2011Article
- Suppressive effects of 1,4-dihydroxy-2-naphthoic acid administration on bone resorption.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2010Article
- Bone mass and microarchitecture of irradiated and bone marrow-transplanted mice: influences of the donor strain.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organ transplantation has become increasingly common as a therapy for end-stage renal, liver, cardiac and pulmonary disease. The population of patients who have survived organ transplantation has grown dramatically over the last 2 decades. Although organ transplant recipients now benefit from greatly improved survival, long-term complications of organ transplantation, such as osteoporosis, adversely affect quality of life and must be addressed. In the early post-transplantation period, the effects of high dose glucocorticoids, combined with other immunosuppressive drugs such as cycosporine A and tacrolimus, cause rapid bone loss particularly at the spine and proximal femur. In this setting, fracture incidence rates as high as 25-65% have been reported. Treatment and prevention strategies must target this early post-transplant period, as well as the patient awaiting transplantation and the long-term transplant recipient. This review will discuss the clinical features of transplantation osteoporosis, the pathophysiology of post-transplantation bone loss and prevention and therapy of this unique bone disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.