Evidence map›Paper›PMID 12906374›Full record

ArticleJournal of endocrinological investigation2003

Interleukin-6 producing pheochromocytoma presenting with acute inflammatory syndrome.

M Minetto, A Dovio, M Ventura, S Cappia, F Daffara, M Terzolo, A Angeli

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Journal of endocrinological investigation, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Pheochromocytoma with fever and iron deficiency anemia.Proceedings (Baylor University. Medical Center) · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Pheochromocytoma: a permanent challenge for the clinical endocrinologist.Journal of endocrinological investigation · 2003
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M MinettoDepartment of clinical and Biological Sciences, General Medical Clinic, San Luigi Hospital, Orbassano (TO), Italy. marcominetto@libero.it
A Dovio
M Ventura
S Cappia
F Daffara
M Terzolo
A Angeli

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pheochromocytomas are tumors able to produce catecholamines and a variety of biologically active neuropeptides. We report the case of a 36-yr-old female patient with pheochromocytoma exhibiting headache, intermittent fever, thrombocytosis, and marked inflammatory signs. Nonsteroidal anti-inflammatory drugs were ineffective in lowering the body temperature, while a corticosteroid agent obtained excellent results. IL-6 was found elevated (20 pg/ml); it fell to 4.5 pg/ml 3 weeks after the adrenalectomy, in parallel to normalization of other laboratory data. The interleukin-6 (IL-6) over-production can either be ascribed directly to the tumor (as confirmed by immunohistochemistry) or indirectly accounted for by tumoral production, as a consequence of the high levels of circulating norepinephrine. To our knowledge, our paper represents the 6th case report of IL-6 secreting pheochromocytoma associated with clinical markers of inflammatory response.

Indexed as

Adrenal Cortex HormonesAdrenalectomyAdrenal Gland NeoplasmsAdultAnti-Inflammatory Agents, Non-SteroidalFemaleFeverHumansInterleukin-6NorepinephrineParaneoplastic SyndromesPheochromocytomaAdrenal Cortex HormonesAnti-Inflammatory Agents, Non-SteroidalInterleukin-6Norepinephrine

Identifiers

PMID12906374

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.