ReviewOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2003
Searching for osteoporosis genes in the post-genome era: progress and challenges.
Review in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between LRP5 polymorphism and bone mineral density: a Bayesian meta-analysis.BMC medical genetics · 2008Pooled it
- MicroRNAs: Harbingers and shapers of periodontal inflammation.Seminars in cell & developmental biology · 2022Review
- Post-GWAS Polygenic Risk Score: Utility and Challenges.JBMR plus · 2020Article
- Article
- Identification of potential pathogenic genes associated with osteoporosis.Bone & joint research · 2017Article
- Computational Characterization of Osteoporosis Associated SNPs and Genes Identified by Genome-Wide Association Studies.PloS one · 2016Article
- Genetic profiling and individualized assessment of fracture risk.Nature reviews. Endocrinology · 2013Review
- Genetics and the individualized prediction of fracture.Current osteoporosis reports · 2012Review
- Bone health - An investment.Indian journal of orthopaedics · 2009Article
- Article
- Hip fracture risk and different gene polymorphisms in the Turkish population.Clinics (Sao Paulo, Brazil) · 2008Article
- PPARG by dietary fat interaction influences bone mass in mice and humans.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2008Article
- Osteoprotegerin Lys3Asn polymorphism and the risk of fracture in older women.The Journal of clinical endocrinology and metabolism · 2008Article
- Studies on the Small Body Size Mouse Developed by MutagenToxicological research · 2008Article
- COL1A1, ESR1, VDR and TGFB1 polymorphisms and haplotypes in relation to BMD in Spanish postmenopausal women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2007Article
- Identification of quantitative trait loci affecting body composition in a mouse intercross.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Molecular genetic studies of gene identification for osteoporosis: a 2004 update.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2006Review
- A functional polymorphism in the PTHR1 promoter region is associated with adult height and BMD measured at the femoral neck in a large cohort of young caucasian women.Human genetics · 2006Article
- Unique and common genetic effects between bone mineral density and calcaneal quantitative ultrasound measures: the Fels Longitudinal Study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2006Article
- The Genetics of PPARG and the Skeleton.PPAR research · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Osteoporosis is a common skeletal disease characterized by low bone mineral density (BMD), deterioration of bone microarchitecture and increased fracture risk. It is a complex disease that has high social and economic costs. Osteoporosis and its associated phenotypes are under the strong genetic control. Identification and characterization of specific loci or genes involved in determining osteoporosis and its associated phenotypes will contribute to a greater understanding of the pathogenesis of osteoporosis, and ultimately might lead to the development of better diagnosis, prevention and treatment strategies. Efforts to identify osteoporosis genes have focused on three approaches: animal models, candidate gene approach, and genome-wide scans. In this article, we review the current status for mapping and identification of genes for osteoporosis, with a focus on some promising regions and future prospects.
Indexed as
Identifiers
12904838What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.