ArticleJournal of clinical microbiology2003
Evidence for genetic linkage between the gene segments encoding NSP4 and VP6 proteins in common and reassortant human rotavirus strains.
Article in Journal of clinical microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Genotyping and Molecular Characterization of VP6 and NSP4 Genes of Unusual Rotavirus Group A Isolated from Children with Acute Gastroenteritis.Advances in virology · 2024Article
- Unusual mono-reassortant of a Wa-like G1P[8] species A rotavirus containing a DS-1-like (genotype 2) NSP4 gene.Virus genes · 2020Article
- Analysis of NSP4 Gene and Its Association with Genotyping of Rotavirus Group A in Stool SamplesIranian biomedical journal · 2018Article
- Distinguishing the genotype 1 genes and proteins of human Wa-like rotaviruses vs. porcine rotaviruses.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2016Article
- Article
- Diversity and relationships of cocirculating modern human rotaviruses revealed using large-scale comparative genomics.Journal of virology · 2012Article
- Putative canine origin of rotavirus strain detected in a child with diarrhea, Taiwan.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2012Article
- Highly sensitive detection of the group A Rotavirus using Apolipoprotein H-coated ELISA plates compared to quantitative real-time PCR.Virology journal · 2011Article
- Detection and characterization of waterborne gastroenteritis viruses in urban sewage and sewage-polluted river waters in Caracas, Venezuela.Applied and environmental microbiology · 2009Article
- Group A human rotavirus genomics: evidence that gene constellations are influenced by viral protein interactions.Journal of virology · 2008Article
- Detection of a porcine-like rotavirus in a child with enteritis in Italy.Journal of clinical microbiology · 2008Article
- Article
- Determination of human rotavirus VP6 genogroups I and II by reverse transcription-PCR.Journal of clinical microbiology · 2008Article
- Molecular epidemiology of rotavirus diarrhea among children in Saudi Arabia: first detection of G9 and G12 strains.Journal of clinical microbiology · 2008Article
- Molecular characterization of G11P[25] and G3P[3] human rotavirus strains associated with asymptomatic infection in South India.Journal of medical virology · 2007Article
- Modification of rotavirus multiplex RT-PCR for the detection of G12 strains based on characterization of emerging G12 rotavirus strains from South India.Journal of medical virology · 2007Article
- Characterization of G10P[11] rotaviruses causing acute gastroenteritis in neonates and infants in Vellore, India.Journal of clinical microbiology · 2004Article
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7 authors.
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Abstract
NSP4-encoding genes of 78 human rotavirus strains of common or reassortant genotypes were characterized by reverse transcription-PCR followed by sequencing and phylogenetic analysis. It was found that all the human strains characterized clustered into only two of the five known NSP4 genotypes. Linkage between NSP4 genotypes and VP6 subgroups was 100%, NSP4 genotype A being linked to VP6 of subgroup I (SGI) and NSP4 of genotype B being linked to VP6 of SGII. The diversity among the NSP4- and VP6-encoding genes was significantly less than that among the VP7 and VP4 genes in cocirculating human rotavirus strains. Whereas G and P types appear to be shared among different animal species and humans, the NSP4- and VP6-encoding genes appear to segregate according to their host of origin, suggesting that these two proteins may be host restriction determinants. The NSP4-VP6 association may be structurally determined during rotavirus replication (morphogenesis).
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