ArticleApplied and environmental microbiology2003
Increased exopolysaccharide production in Lactococcus lactis due to increased levels of expression of the NIZO B40 eps gene cluster.
Article in Applied and environmental microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 58 citations in OpenAlex.
- Members of theMicrobial genomics · 2026Article
- Diverse Repertoire and Relationship of Exopolysaccharide Genes in Cold-AdaptedMicroorganisms · 2023Article
- Effects of galactosyltransferase on EPS biosynthesis and freeze-drying resistance ofFood chemistry. Molecular sciences · 2022Article
- Expression of genes involved in exopolysaccharide synthesis in Lactiplantibacillus plantarum VAL6 under environmental stresses.Archives of microbiology · 2021Article
- Proteomic analysis reveals potential factors associated with enhanced EPS production in Streptococcus thermophilus ASCC 1275.Scientific reports · 2020Article
- Systems Biology - A Guide for Understanding and Developing Improved Strains of Lactic Acid Bacteria.Frontiers in microbiology · 2019Review
- Altering textural properties of fermented milk by using surface-engineered Lactococcus lactis.Microbial biotechnology · 2018Article
- Relationship Between PutativeFrontiers in microbiology · 2018Article
- Comparative mRNA-Seq Analysis Reveals the Improved EPS Production Machinery inFrontiers in microbiology · 2018Article
- EpsA is an essential gene in exopolysaccharide production in Lactobacillus johnsonii FI9785.Microbial biotechnology · 2016Article
- Exopolysaccharide production and ropy phenotype are determined by two gene clusters in putative probiotic strain Lactobacillus paraplantarum BGCG11.Applied and environmental microbiology · 2015Article
- Characterization of an Ebosin derivative produced by heterologous gene replacement in Streptomyces sp. 139.Microbial cell factories · 2014Article
- Enhancement of Exopolysaccharide Production of Lactobacillus fermentum TDS030603 by Modifying Culture Conditions.Bioscience of microbiota, food and health · 2014Article
- Characterization of plasmid pML21 of Enterococcus faecalis ML21 from koumiss.Current microbiology · 2013Article
- In silico reconstruction of the metabolic pathways of Lactobacillus plantarum: comparing predictions of nutrient requirements with those from growth experiments.Applied and environmental microbiology · 2005Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exopolysaccharides (EPS) play an important role in the rheology and texture of fermented food products. This is the first report demonstrating that homologous overexpression of a complete eps gene cluster in Lactococcus lactis leads to increased EPS production levels. A ninefold-elevated EPS plasmid copy number led to an almost threefold increase in the eps expression level, resulting in an almost fourfold increase in the NIZO B40 EPS production level. It was previously reported that increased EPS precursor levels did not influence NIZO B40 EPS production levels. However, the present results indicate that the maximal NIZO B40 EPS production level is limited by the activity level of the expression products of the eps gene cluster rather than by the level of EPS precursors.
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