ArticleThe Plant cell2003
An Arabidopsis mutant resistant to thaxtomin A, a cellulose synthesis inhibitor from Streptomyces species.
Article in The Plant cell, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 195 citations in OpenAlex.
- When, where, and why specialised metabolites are produced: inferring function from expression control.Essays in biochemistry · 2026Review
- A STRUBBELIG-NHL3 cell surface receptor complex mediates the response to cellulose deficiency in Arabidopsis.Nature plants · 2026Article
- A molecular description of plant cellulose biosynthesis inhibition.bioRxiv : the preprint server for biology · 2026Article
- A fungal natural product that inhibits plant cellulose biosynthesis by disrupting cellulose synthase complexes.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Chromosome-level genome assembly and annotation of a novel potato common scab pathogen.Frontiers in plant science · 2026Article
- An integrated AI knowledge graph framework of bacterial enzymology and metabolism.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Deciphering metabolite signalling between plant roots and soil pathogens to design resistance.BMC plant biology · 2025Review
- The Silencing of theInternational journal of molecular sciences · 2025Article
- Genome-Wide Genetic Architecture for Common Scab (International journal of molecular sciences · 2025Article
- The fnr-like mutants confer isoxaben tolerance by initiating mitochondrial retrograde signalling.Plant biotechnology journal · 2024Article
- Bacterial diversity, community structure and function in association of potato scabby tubers during storage in northern Thailand.Folia microbiologica · 2024Article
- Cellulose biosynthesis inhibitor isoxaben causes nutrient-dependent and tissue-specific Arabidopsis phenotypes.Plant physiology · 2024Article
- Proteomics fingerprinting reveals importance of iron and oxidative stress inFrontiers in microbiology · 2024Article
- Deciphering host-pathogen interaction during Streptomyces spp. infestation of potato.Archives of microbiology · 2023Review
- Article
- Reduced coenzyme Q synthesis confers non-target site resistance to the herbicide thaxtomin A.PLoS genetics · 2023Article
- ThePlants (Basel, Switzerland) · 2022Article
- Antiamoebic Properties of Laboratory and Clinically Used Drugs against Naegleria fowleri and Balamuthia mandrillarisAntibiotics (Basel, Switzerland) · 2022Article
- iTRAQ-Based Proteomics Analysis of Response toInternational journal of molecular sciences · 2021Article
- Identification of Novel Rotihibin Analogues inMicrobiology spectrum · 2021Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thaxtomin A is a phytotoxin produced by Streptomyces scabies and other Streptomyces species, the causative agents of common scab disease in potato and other taproot crops. At nanomolar concentrations, thaxtomin causes dramatic cell swelling, reduced seedling growth, and inhibition of cellulose synthesis in Arabidopsis. We identified a mutant of Arabidopsis, designated txr1, that exhibits increased resistance to thaxtomin as a result of a decrease in the rate of toxin uptake. The TXR1 gene was identified by map-based cloning and found to encode a novel, small protein with no apparent motifs or organelle-targeting signals. The protein, which has homologs in all fully sequenced eukaryotic genomes, is expressed in all tissues and during all developmental stages analyzed. Microarray transcript profiling of some 14,300 genes revealed two stomatin-like genes that were expressed differentially in the txr1 mutant and the wild type. We propose that TXR1 is a regulator of a transport mechanism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.