Evidence map›Paper›PMID 12897024›Full record

ArticleJournal of bacteriology2003

Escherichia coli cells bearing a ribosomal ambiguity mutation in rpsD have a mutator phenotype that correlates with increased mistranslation.

Sergey Balashov, M Zafri Humayun

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Stress-Induced Mutagenesis.EcoSal Plus · 2012
    Article
  8. Article
  9. Review
  10. Article
  11. Inhibited cell growth and protein functional changes from an editing-defective tRNA synthetase.Proceedings of the National Academy of Sciences of the United States of America · 2005
    Article
  12. Stress-induced mutagenesis in bacteria.Critical reviews in biochemistry and molecular biology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sergey BalashovUniversity of Medicine and Dentistry of New Jersey--New Jersey Medical School, Department of Microbiology and Molecular Genetics, International Center for Public Health, Newark, New Jersey 07101-1709, USA.
M Zafri Humayun
International Center for Public Health · USRutgers New Jersey Medical School

Funding

MECHANISMS OF MISTRANSLATION MEDIATED MUTATOR RESPONSER01GM058253 · NIGMS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI HUMAYUN, M. ZAFRI · 1998 to 2009
$1.6M
NIGMS NIH HHS GM58253NIGMS NIH HHS R01 GM058253
6 · The paper itself

Abstract

Escherichia coli cells bearing certain mutations in rpsD (coding for the 30S ribosomal protein S4) show a ribosomal ambiguity (Ram) phenotype characterized by increased translational error rates. Here we show that spontaneous mutagenesis increases in Ram cells bearing the rpsD14 allele, suggesting that the recently described translational stress-induced mutagenesis pathway is activated in Ram cells.

Indexed as

MutationProtein BiosynthesisAnti-Bacterial AgentsEscherichia coliMicrobial Sensitivity TestsPhenotypeRibosomal ProteinsStreptomycinAnti-Bacterial AgentsRibosomal Proteinsribosomal protein S4Streptomycin

Identifiers

PMID12897024
PMCPMC166475
OpenAlexW2112833616

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.