Evidence map›Paper›PMID 12897021›Full record

ArticleJournal of bacteriology2003

Mutational analysis of cell wall biosynthesis in Mycobacterium avium.

Jean-Pierre Laurent, Kirsten Hauge, Kellie Burnside, Gerard Cangelosi

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Journal of clinical tuberculosis and other mycobacterial diseases · 2024
    Article
  2. Liposomal drug delivery to manage nontuberculous mycobacterial pulmonary disease and other chronic lung infections.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  3. Review
  4. Mutation onVirulence · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jean-Pierre LaurentSeattle Biomedical Research Institute, Seattle, Washington 98109, USA.
Kirsten Hauge
Kellie Burnside
Gerard Cangelosi
Center for Infectious Disease Research · US

Funding

Diseases of Public Health Importance Training GrantT32AI007509 · NIAID · UNIVERSITY OF WASHINGTON · PI LUND, JENNIFER M · 1997 to 2024
$6.3M
NIAID NIH HHS AI25767NIAID NIH HHS T32 AI007509NIAID NIH HHS T32AI07509
6 · The paper itself

Abstract

The cell wall of the environmental pathogen Mycobacterium avium is important to its virulence and intrinsic antimicrobial resistance. To identify genes involved in cell wall biosynthesis, "transposome" insertion libraries were screened for mutants with altered colony morphology on medium containing the lipoprotein stain Congo red. Nineteen such mutants were isolated and mapped, including 10 with insertions in a functional island of cell wall biosynthetic genes that spans approximately 40 kb of the M. avium genome.

Indexed as

Bacterial ProteinsCell WallCongo RedDNA Transposable ElementsGene LibraryGlycolipidsGlycopeptidesMutagenesis, InsertionalMutationMycobacterium aviumBacterial ProteinsCongo RedDNA Transposable ElementsGlycolipidsGlycopeptides

Identifiers

PMID12897021
PMCPMC166487
OpenAlexW2049598908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.