ArticleJournal of anatomy2003
The detection of mature T- and B-cells during development of the lymphoid tissues of the tammar wallaby (Macropus eugenii).
Article in Journal of anatomy, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 37 citations in OpenAlex.
- Review
- Opossum Mammary Maturation as It Relates to Immune Cell Infiltration and Nutritional Gene Transcription.Integrative organismal biology (Oxford, England) · 2020Article
- γδ T cells are the predominant T cell type in opossum mammaries during lactation.Developmental and comparative immunology · 2019Article
- Functional Conservation of a Developmental Switch in Mammals since the Jurassic Age.Molecular biology and evolution · 2019Article
- On the prenatal initiation of T cell development in the opossum Monodelphis domestica.Journal of anatomy · 2017Article
- Characterisation of the immune compounds in koala milk using a combined transcriptomic and proteomic approach.Scientific reports · 2016Article
- The identification of immune genes in the milk transcriptome of the Tasmanian devil (Sarcophilus harrisii).PeerJ · 2016Article
- Immunological Insights into the Life and Times of the Extinct Tasmanian Tiger (Thylacinus cynocephalus).PloS one · 2015Article
- Identification of dendritic cells, B cell and T cell subsets in Tasmanian devil lymphoid tissue; evidence for poor immune cell infiltration into devil facial tumors.Anatomical record (Hoboken, N.J. : 2007) · 2014Article
- Early postnatal B cell ontogeny and antibody repertoire maturation in the opossum, Monodelphis domestica.PloS one · 2012Article
- Transcriptomic analysis supports similar functional roles for the two thymuses of the tammar wallaby.BMC genomics · 2011Article
- Ancient antimicrobial peptides kill antibiotic-resistant pathogens: Australian mammals provide new options.PloS one · 2011Article
- Culture and stimulation of tammar wallaby lymphocytes.Veterinary research communications · 2007Article
- The appearance and distribution of mature T and B cells in the developing immune tissues of the stripe-faced dunnart (Sminthopsis macroura).Journal of anatomy · 2004Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The distribution of T- and B-cells in the developing lymphoid and immunohaematopoietic tissues of the tammar wallaby were investigated using antibodies to the mature cell surface markers, CD3, CD5 and CD79b. In the thymus, CD3- and CD5-positive T-cells were first observed at day 12 postpartum whilst rare B-cells were first detected at day 23. Both T- and B-lymphocytes were first stained on day 21 postpartum in the spleen and day 24 in lymph nodes. In one sample from a 7-day-old animal, rare CD79b-positive (CD79b+) lymphocytes were observed in the gut-associated lymphoid tissues. However, CD3+ cells were not apparent until day 12 and CD5+ cells were not detected until day 74 postpartum. No lymphocytes were detected in liver or bone marrow samples and no bronchus-associated lymphoid tissues were observed. The pattern of development and the distribution of T- and B-cells in the lymphoid and immunohaematopoietic tissues were similar to those observed in eutherian mammals and in limited studies of other metatherians. However, the detection of apparently mature T- and B-cells in the thymus and gut-associated lymphoid tissues (GALT) at the same postnatal age highlights the need for a more substantial study of the development of GALT. This is, at present, limited by availability of marsupial-specific antibodies.
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