Evidence map›Paper›PMID 12890838›Full record

ArticleThe New England journal of medicine2003

The von Hippel-Lindau protein, vascular endothelial growth factor, and kidney cancer.

Daniel J George, William G Kaelin

Registry-linked trialAbstract readComment
PubMed Publisher
In one paragraph

Article in The New England journal of medicine, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04462445 (Prospective Translational Study Investigating Possible Molecular prEdictors of Resistance to First-Line pazopanIb in Metastatic reNal Cell Carcinoma), which is not on this map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04462445 phase2completednot on this mapstarted 2015, after this paper: background citation

Prospective Translational Study Investigating Possible Molecular prEdictors of Resistance to First-Line pazopanIb in Metastatic reNal Cell Carcinoma

TypeinterventionalSponsorFondazione IRCCS Istituto Nazionale dei Tumori, MilanoRan2015 to 2017Enrolled25ConditionsMetastatic Renal Cell CarcinomaArmsPazopanib
3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Trial
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  11. Molecular Mechanisms and Future Implications of VEGF/VEGFR in Cancer Therapy.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Management of metastatic renal cell carcinoma - mini review.Journal of kidney cancer and VHL · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Daniel J GeorgeDana-Farber Cancer Institute, Boston, USA.
William G Kaelin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Tumor Suppressor ProteinsUbiquitin-Protein LigasesAdenocarcinoma, Clear CellAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedBevacizumabCarcinoma, Renal CellDisease-Free SurvivalEndothelial Growth FactorsGene SilencingGenes, Tumor SuppressorHumansIntercellular Signaling Peptides and ProteinsKidney NeoplasmsLigasesLymphokinesAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedBevacizumabEndothelial Growth FactorsIntercellular Signaling Peptides and ProteinsLigasesLymphokinesTumor Suppressor ProteinsUbiquitin-Protein LigasesVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsVHL protein, humanVon Hippel-Lindau Tumor Suppressor Protein

Identifiers

PMID12890838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.