ArticleEmerging infectious diseases2003
Sulfa resistance and dihydropteroate synthase mutants in recurrent Pneumocystis carinii pneumonia.
Article in Emerging infectious diseases, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 50 citations in OpenAlex.
- Molecular mechanisms of acquired antifungal drug resistance in principal fungal pathogens and EUCAST guidance for their laboratory detection and clinical implications.The Journal of antimicrobial chemotherapy · 2022Review
- Selection ofJournal of fungi (Basel, Switzerland) · 2021Article
- Consensus Multilocus Sequence Typing Scheme forJournal of fungi (Basel, Switzerland) · 2020Review
- Therapy and Management ofJournal of fungi (Basel, Switzerland) · 2018Review
- A Molecular Window into the Biology and Epidemiology of Pneumocystis spp.Clinical microbiology reviews · 2018Review
- High transient colonization by Pneumocystis jirovecii between mothers and newborn.European journal of pediatrics · 2017Article
- A Case of Pneumonia Caused by Pneumocystis jirovecii Resistant to Trimethoprim-Sulfamethoxazole.The Korean journal of parasitology · 2015Article
- Chitinases in Pneumocystis carinii pneumonia.Medical microbiology and immunology · 2012Article
- Management of Pneumocystis Jirovecii pneumonia in HIV infected patients: current options, challenges and future directions.HIV/AIDS (Auckland, N.Z.) · 2010Article
- Clinical significance and phylogenetic relationship of novel Australian Pneumocystis jirovecii genotypes.Journal of clinical microbiology · 2009Article
- Mutations in the Pneumocystis jirovecii DHPS gene confer cross-resistance to sulfa drugs.Antimicrobial agents and chemotherapy · 2005Article
- Mutations of Pneumocystis jirovecii dihydrofolate reductase associated with failure of prophylaxis.Antimicrobial agents and chemotherapy · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Failure of sulfa or sulfone prophylaxis is associated with mutations in Pneumocystis carinii gene coding for dihydropteroate synthase (DHPS). The DHPS genotype was analyzed in AIDS patients who had two separate episodes of P. carinii pneumonia. The results suggest that DHPS mutations can be selected de novo within patients by the pressure of a sulfa or sulfone drug.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.