Evidence map›Paper›PMID 12888289›Full record

ArticleTrends in cell biology2003

An uncertainty principle in chromosome positioning.

Luis A Parada, Jeffrey J Roix, Tom Misteli

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in cell biology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Mitotic Antipairing of Homologous Chromosomes.Results and problems in cell differentiation · 2022
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. The Three-Dimensional Organization of Mammalian Genomes.Annual review of cell and developmental biology · 2017
    Review
  10. Mechanobiology of Chromatin and the Nuclear Interior.Cellular and molecular bioengineering · 2016
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Long-Range Chromatin Interactions.Cold Spring Harbor perspectives in biology · 2015
    Review
  16. An Overview of Genome Organization and How We Got There: from FISH to Hi-C.Microbiology and molecular biology reviews : MMBR · 2015
    Review
  17. Review
  18. Article
  19. The hierarchy of the 3D genome.Molecular cell · 2013
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Luis A ParadaNational Cancer Institute, Bethesda, MD 20892, USA.
Jeffrey J Roix
Tom Misteli
National Cancer Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromosomes are non-randomly positioned in the mammalian interphase nucleus. It is not known how patterns of chromosome positions are established or to what degree spatial arrangements of chromosomes change during the cell cycle, especially during mitosis. Two reports have applied in vivo microscopy to track chromosomes in space and time. The results highlight the inherently imperfect and probabilistic nature of chromosome positioning in the cell nucleus.

Indexed as

AnimalsCell CycleCell DivisionCentromereChromatinChromosome PositioningFluorescence Recovery After PhotobleachingHumansInterphaseIntranuclear SpaceLuminescent ProteinsMicroscopy, FluorescenceMitosisModels, BiologicalChromatinLuminescent Proteins

Identifiers

PMID12888289
OpenAlexW2050479831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.