Evidence map›Paper›PMID 12885982›Full record

Trial reportThorax2003

Effect of two breathing exercises (Buteyko and pranayama) in asthma: a randomised controlled trial.

S Cooper, J Oborne, S Newton, V Harrison, J Thompson Coon, S Lewis, A Tattersfield

2 registry-linked trialsOpen access · bronzeAbstract readClinical TrialRandomized Controlled Trial
In one paragraph

Trial report in Thorax, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 36 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 7 pooled it
21.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04110951 nacompletednot on this mapstarted 2018, after this paper: background citation

The Effect of Pranayama Breathing Technique on Asthma Control, Pulmonary Function and Quality of Life: A Single-Blind Randomized Controlled Trial

TypeinterventionalSponsorTC Erciyes UniversityRan2018 to 2019Enrolled50ConditionsAsthmaArmsPranayama Breathing Technique, Relaxation technique
NCT05593315 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Efficacy of the Combination of General Relaxation (Mindfulness) and Respiratory (Buteyko) Techniques for the Improvement of Poorly Controlled Asthma. The MBA Study

TypeinterventionalSponsorFundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauRan2023 to 2025Enrolled40ConditionsAsthma, Anxiety, StressArmsMindfulness and Buteyko techniques
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 7 syntheses or guidelines pooled it, 211 citations in OpenAlex.

  1. Breathing techniques to reduce symptoms in people with serious respiratory illness: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
  2. Breathing exercises for adults with asthma.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Yoga for asthma.The Cochrane database of systematic reviews · 2016
    Pooled it
  4. Breathing exercises for children with asthma.The Cochrane database of systematic reviews · 2016
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Psychosocial factors and behavioral medicine interventions in asthma.Journal of consulting and clinical psychology · 2013
    Pooled it
  8. Trial
  9. Trial
  10. Yoga Therapy as an Adjuvant in Management of Asthma.Indian journal of pediatrics · 2021
    Trial
  11. Trial
  12. The BREATHE study: Breathing REtraining for Asthma--Trial of Home Exercises. a protocol summary of a randomised controlled trial.Primary care respiratory journal : journal of the General Practice Airways Group · 2013
    Trial
  13. Trial
  14. Characteristics of yoga users: results of a national survey.Journal of general internal medicine · 2008
    Trial
  15. Trial
  16. Trial
  17. Article
  18. Article
  19. Review
  20. Visual biofeedback for paradoxical vocal fold motion (PVFM).Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

S CooperDivision of Respiratory Medicine, City Hospital, Nottingham NG5 1PB, UK. sue.cooper@nottingham.ac.uk
J Oborne
S Newton
V Harrison
J Thompson Coon
S Lewis
A Tattersfield
Nottingham City Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with asthma are interested in the use of breathing exercises but their role is uncertain. The effects of the Buteyko breathing technique, a device which mimics pranayama (a yoga breathing technique), and a dummy pranayama device on bronchial responsiveness and symptoms were compared over 6 months in a parallel group study.

methodsNinety patients with asthma taking an inhaled corticosteroid were randomised after a 2 week run in period to Eucapnic Buteyko breathing, use of a Pink City Lung Exerciser (PCLE) to mimic pranayama, or a PCLE placebo device. Subjects practised the techniques at home twice daily for 6 months followed by an optional steroid reduction phase. Primary outcome measures were symptom scores and change in the dose of methacholine provoking a 20% fall in FEV(1) (PD(20)) during the first 6 months.

resultsSixty nine patients (78%) completed the study. There was no significant difference in PD(20) between the three groups at 3 or 6 months. Symptoms remained relatively stable in the PCLE and placebo groups but were reduced in the Buteyko group. Median change in symptom scores at 6 months was 0 (interquartile range -1 to 1) in the placebo group, -1 (-2 to 0.75) in the PCLE group, and -3 (-4 to 0) in the Buteyko group (p=0.003 for difference between groups). Bronchodilator use was reduced in the Buteyko group by two puffs/day at 6 months; there was no change in the other two groups (p=0.005). No difference was seen between the groups in FEV(1), exacerbations, or ability to reduce inhaled corticosteroids.

conclusionThe Buteyko breathing technique can improve symptoms and reduce bronchodilator use but does not appear to change bronchial responsiveness or lung function in patients with asthma. No benefit was shown for the Pink City Lung Exerciser.

Indexed as

Breathing ExercisesAdrenergic beta-AgonistsAdultAlgorithmsAsthmaFemaleForced Expiratory VolumeHumansMaleMiddle AgedPatient SatisfactionSteroidsTreatment OutcomeVital CapacityAdrenergic beta-AgonistsSteroids

Identifiers

PMID12885982
PMCPMC1746772
OpenAlexW2131123946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.