Evidence map›Paper›PMID 12885631›Full record

ArticleBiophysical journal2003

The motility of mollicutes.

Charles W Wolgemuth, Oleg Igoshin, George Oster

Open access · bronzeAbstract readComparative StudyEvaluation StudyValidation Study
In one paragraph

Article in Biophysical journal, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Charles W WolgemuthDepartment of Physiology, University of Connecticut Health Center, Farmington, Connecticut, USA.
Oleg Igoshin
George Oster
University of California, Berkeley · USUConn Health · US

Funding

MOLECULAR BIOMECHANICSR01GM059875 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI OSTER, GEORGE F · 2000 to 2004
$957k
NIGMS NIH HHS GM59875-02NIGMS NIH HHS R01 GM059875
6 · The paper itself

Abstract

Recent experiments show that the conformation of filament proteins play a role in the motility and morphology of many different types of bacteria. Conformational changes in the protein subunits may produce forces to drive propulsion and cell division. Here we present a molecular mechanism by which these forces can drive cell motion. Coupling of a biochemical cycle, such as ATP hydrolysis, to the dynamics of elastic filaments enable elastic filaments to propagate deformations that generate propulsive forces. We demonstrate this possibility for two classes of wall-less bacteria called mollicutes: the swimming of helical-shaped Spiroplasma, and the gliding motility of Mycoplasma.

Indexed as

Bacterial Physiological PhenomenaModels, BiologicalMotionComputer SimulationMechanotransduction, CellularModels, ChemicalMolecular Motor ProteinsMycoplasmaSpecies SpecificitySpiroplasmaStress, MechanicalSwimmingTenericutesMolecular Motor Proteins

Identifiers

PMID12885631
PMCPMC1303205
OpenAlexW2032710208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.