ArticleMolecular genetics and genomics : MGG2003
An integrated physical and genetic map of the nematode Pristionchus pacificus.
Article in Molecular genetics and genomics : MGG, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Analysis of meiosis ineLife · 2021Article
- A Genome Resequencing-Based Genetic Map Reveals the Recombination Landscape of an Outbred Parasitic Nematode in the Presence of Polyploidy and Polyandry.Genome biology and evolution · 2018Article
- Chromatin remodelling and antisense-mediated up-regulation of the developmental switch gene eud-1 control predatory feeding plasticity.Nature communications · 2016Article
- Gene inactivation using the CRISPR/Cas9 system in the nematode Pristionchus pacificus.Development genes and evolution · 2015Article
- Article
- Microevolution of Duplications and Deletions and Their Impact on Gene Expression in the Nematode Pristionchus pacificus.PloS one · 2015Article
- Characterization of genetic diversity in the nematode Pristionchus pacificus from population-scale resequencing data.Genetics · 2014Article
- A hybrid BAC physical map of potato: a framework for sequencing a heterozygous genome.BMC genomics · 2011Article
- Sequence-based physical mapping of complex genomes by whole genome profiling.Genome research · 2011Article
- Genome-wide survey and analysis of microsatellites in nematodes, with a focus on the plant-parasitic species Meloidogyne incognita.BMC genomics · 2010Article
- Genomic linkage map of the human blood fluke Schistosoma mansoni.Genome biology · 2009Article
- Phylogeny of the nematode genus Pristionchus and implications for biodiversity, biogeography and the evolution of hermaphroditism.BMC evolutionary biology · 2007Article
- Pristionchus.org: a genome-centric database of the nematode satellite species Pristionchus pacificus.Nucleic acids research · 2007Article
- Sex, bugs and Haldane's rule: the nematode genus Pristionchus in the United States.Frontiers in zoology · 2006Article
- On the maximal cliques in c-max-tolerance graphs and their application in clustering molecular sequences.Algorithms for molecular biology : AMB · 2006Article
- Conservation of the global sex determination gene tra-1 in distantly related nematodes.Genes & development · 2004Article
- Evolution of dnmt-2 and mbd-2-like genes in the free-living nematodes Pristionchus pacificus, Caenorhabditis elegans and Caenorhabditis briggsae.Nucleic acids research · 2004Article
- AppaDB: an AcedB database for the nematode satellite organism Pristionchus pacificus.Nucleic acids research · 2004Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The free-living nematode Pristionchus pacificus is one of several species that have recently been developed as a satellite system for comparative functional studies in evolutionary developmental biology. Comparisons of developmental processes between P. pacificus and the well established model organism Caenorhabditis elegans at the cellular and genetic levels provide detailed insight into the molecular changes that shape evolutionary transitions. To facilitate genetic analysis and cloning of mutations in P. pacificus, we previously generated a BAC-based genetic linkage map for this organism. Here, we describe the construction of a physical map of the P. pacificus genome based on AFLP fingerprint analysis of 7747 BAC clones. Most of the SSCP markers used to generate the genetic linkage map were derived from BAC ends, so that the physical genome map and the genetic map can be integrated. The contigs that make up the physical map are evenly distributed over the genetic linkage map and no clustering is observed, indicating that the physical map provides a valid representation of the P. pacificus genome. The integrated genome map thus provides a framework for positional cloning and the study of genome evolution in nematodes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.