ArticleJournal of epidemiology and community health2003
An adaptation of the Framingham coronary heart disease risk function to European Mediterranean areas.
Article in Journal of epidemiology and community health, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 99 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving Intermediate Risk Management. MARK Study
BASALTO (Bariatric Surgery and LDL Cholesterol) Trial
Who cites it
99 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Assessment of the value of a genetic risk score in improving the estimation of coronary risk.Atherosclerosis · 2012Pooled it
- Cardiovascular risk after bariatric surgery for obesity.The American journal of cardiology · 2008Pooled it
- Short-term effects of gastric bypass versus sleeve gastrectomy on high LDL cholesterol: The BASALTO randomized clinical trial.Cardiovascular diabetology · 2024Trial
- Capacity adiposity indices to identify metabolic syndrome in subjects with intermediate cardiovascular risk (MARK study).PloS one · 2019Trial
- Cardiovascular disease risk and comparison of different strategies for blood pressure management in rural India.BMC public health · 2018Trial
- Prediction of Cardiovascular Disease by the Framingham-REGICOR Equation in the High-Risk PREDIMED Cohort: Impact of the Mediterranean Diet Across Different Risk Strata.Journal of the American Heart Association · 2017Trial
- Glycemic markers and relation with arterial stiffness in Caucasian subjects of the MARK study.PloS one · 2017Trial
- Association between markers of glycemia and carotid intima-media thickness: the MARK study.BMC cardiovascular disorders · 2016Trial
- Trial
- Chronic kidney disease in the type 2 diabetic patients: prevalence and associated variables in a random sample of 2642 patients of a Mediterranean area.BMC nephrology · 2012Trial
- Improving interMediAte risk management. MARK study.BMC cardiovascular disorders · 2011Trial
- Cohort Profile: The Girona Heart Registry.International journal of epidemiology · 2025Article
- Pulse Wave Velocity Assessment: A Useful Tool to Screen Asymptomatic Individuals at High Cardiovascular Risk?Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Persistent inflammatory activation in people living with HIV. Involvement in atherosclerosis.Frontiers in medicine · 2025Article
- Health program for prEvention of cardiovascuLar disEases based on a risk screeNing strategy with Ankle-brachial index: HELENA study protocol.Frontiers in public health · 2025Article
- Article
- Article
- Bone proteins are associated with cardiovascular risk according to the SCORE2-Diabetes algorithm.Cardiovascular diabetology · 2024Article
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- Predictive Score for Advanced Colorectal Neoplasia Based on Cardiovascular and Colorectal Cancer Risk Factors.Journal of clinical medicine · 2024Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo determine whether the Framingham function accurately predicts the 10 year risk of coronary disease and to adapt this predictive method to the characteristics of a Spanish population. METHOD AND
resultsA Framingham function for predicting 10 year coronary deaths and non-fatal myocardial infarction was applied to the population of the province of Gerona, Spain, where the cumulated incidence rate of myocardial infarction has been determined since 1988 by a specific registry. The prevalence of cardiovascular risk factors in this region of Spain was established in 1995 by a cross sectional study on a representative sample of 1748 people. The number of cases estimated by the Framingham function for 10 year coronary deaths and non-fatal myocardial infarction was compared with that observed. The Framingham function estimated 2425 coronary heart disease cases in women and 1181 were observed. In men, 9919 were estimated and 3706 were observed. Recalibrating the Framingham equations to the event rate and the prevalence of the risk factors in Gerona led to estimates very close to the number of cases observed in Gerona men and women.
conclusionsThe Framingham function estimates more than doubled the actual risk of coronary disease observed in north east Spain. After calibration, the Framingham function became an effective method of estimating the risk in this region with low coronary heart disease incidence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.