ReviewCerebellum (London, England)2002
The beta-thymosins, small actin-binding peptides widely expressed in the developing and adult cerebellum.
Review in Cerebellum (London, England), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 33 citations in OpenAlex.
- Thymosin Beta 4 Protects Hippocampal Neuronal Cells against PrP (106-126) via Neurotrophic Factor Signaling.Molecules (Basel, Switzerland) · 2023Article
- Exploring the Mechanisms of Electroacupuncture-Induced Analgesia through RNA Sequencing of the Periaqueductal Gray.International journal of molecular sciences · 2017Article
- Thymosin β4 overexpression regulates neuron production and spatial distribution in the developing avian optic tectum.Histochemistry and cell biology · 2017Article
- Effects of acidic peptide size and sequence on trivalent praseodymium adduction and electron transfer dissociation mass spectrometry.Journal of mass spectrometry : JMS · 2017Article
- Immunoreactivity for thymosin beta 4 and thymosin beta 10 in the adult rat oro-gastro-intestinal tract.European journal of histochemistry : EJH · 2013Article
- Thymosin beta4 improves functional neurological outcome in a rat model of embolic stroke.Neuroscience · 2010Article
- Thymosin beta4: a candidate for treatment of stroke?Annals of the New York Academy of Sciences · 2010Article
- The promotive effects of thymosin beta4 on neuronal survival and neurite outgrowth by upregulating L1 expression.Neurochemical research · 2008Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The beta-thymosins are a highly conserved family of small polar peptides known to bind monomeric actin and inhibit its polymerization. The beta-thymosins show a high degree of sequence conservation among all vertebrate classes and they have been also identified in some invertebrate phyla. The most abundant beta-thymosins in mammals are thymosin beta4 (Tbeta4) and thymosin beta10 (Tbeta10), two ubiquitous small (43 amino acids) peptides sharing a high degree of sequence homology. Both beta-thymosins are present in virtually all mammalian tissues and cells studied, showing distinct patterns of expression in several tissues. The beta-thymosins are expressed in the developing and mature nervous system, indicating their participation with other actin-binding peptides in the control of actin polymerization. In the rat cerebellum the temporal and cellular patterns of expression of Tbeta4 and Tbeta10 are different, suggesting that each beta-thymosin could play a specific physiological function during cerebellum development. The possible roles of beta-thymosins in the developing mammalian cerebellum are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.