Evidence map›Paper›PMID 12880353›Full record

ArticleJournal of biomedical optics2003

Metal-enhanced emission from indocyanine green: a new approach to in vivo imaging.

Joanna Malicka, Ignacy Gryczynski, Chris D Geddes, Joseph R Lakowicz

Abstract readComparative StudyEvaluation StudyValidation Study
In one paragraph

Article in Journal of biomedical optics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Metal-enhanced fluorescence of single green fluorescent protein (GFP).Biochemical and biophysical research communications · 2008
    Article
  14. Article
  15. Article
  16. Review
  17. Metal-Enhanced Fluorescence of Phycobiliproteins from Heterogeneous Plasmonic Nanostructures.The journal of physical chemistry. C, Nanomaterials and interfaces · 2007
    Article
  18. Low temperature metal-enhanced fluorescence.Journal of fluorescence · 2007
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joanna MalickaUniversity of Maryland School of Medicine, Department of Biochemistry & Molecular Biology, Center for Fluorescence Spectroscopy, 725 W. Lombard Street, Baltimore, Maryland 21201-1503, USA.
Ignacy Gryczynski
Chris D Geddes
Joseph R Lakowicz

Funding

WHO'S WHO IN FLUORESCENCEP41RR008119 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI CHEUNG, HERBERT C · 1993 to 2006
$7.4M
NCI NIH HHS CA-100982NCRR NIH HHS P41 RR008119NCRR NIH HHS RR-08119
6 · The paper itself

Abstract

Indocyanine green (ICG) is widely used in medical imaging and testing. Its complex spectral behavior and low quantum yield limits some applications. We show that proximity of ICG to a metallic silver particle increases its intensity approximately 20-fold and decreases the decay time. Since the rate of photobleaching is not increased, our results suggest that ICG-silver particle complexes can yield at least 20-fold more photons per ICG molecule for improved medical imaging.

Indexed as

Models, ChemicalComputer SimulationFluorescenceHumansIndocyanine GreenMacromolecular SubstancesMetalsProtein BindingSerum AlbuminSilverSpectrometry, FluorescenceIndocyanine GreenMacromolecular SubstancesMetalsSerum AlbuminSilver

Identifiers

PMID12880353
PMCPMC6942523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.