Evidence map›Paper›PMID 12879971›Full record

ReviewCerebellum (London, England)

The great gate: control of sensory information flow to the cerebellum.

Anna Devor

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cerebellum (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Developmentally Unique Cerebellar Processing Prioritizes Self- over Other-Generated Movements.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Respiratory rhythm generation in vivo.Physiology (Bethesda, Md.) · 2014
    Review
  11. Article
  12. Review
  13. Removal of default state-associated inhibition during repetition priming improves response articulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. In vivo mouse inferior olive neurons exhibit heterogeneous subthreshold oscillations and spiking patterns.Proceedings of the National Academy of Sciences of the United States of America · 2007
    Article
  20. Cerebellar control of the inferior olive.Cerebellum (London, England) · 2006
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Anna DevorDepartment of Neurobiology, Institute of Life Sciences Hebrew University of Jerusalem, Jerusalem 91904, Israel. annakn@lobster.ls.huji.ac.il

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An evident feature of the physiology of the inferior olivary nucleus is modulation of the responsiveness of neurons to peripheral stimulation by the behavioral state of the subject animal. The olivary response to self-generated sensory inputs, as well as to input predictable from association with other stimuli, is suppressed. This suppression occurs in part at the level of the inferior olivary nucleus itself. On the other hand, the cells respond readily to sensory inputs that are not anticipated. On a cellular level inferior olivary neurons exhibit two properties that might account for information gating. The first one is the organization of synaptic inputs on olivary spines in glomerular structures, where extrinsic inhibitory and excitatory inputs, confined to the same olivary dendritic spine, can efficiently cancel each other if they arrive within a certain time window. About half of the inhibitory inputs to olivary glomeruli originate in the deep cerebellar nuclei and are regarded as an inhibitory feedback. The second property is subthreshold membrane potential oscillations, a property of the electrotonically coupled olivary network. Extrinsic synaptic inputs to the nucleus modulate the subthreshold oscillations, and consequently, the response properties of olivary neurons. A considerable amount of indirect evidence indicates that the occurrence of oscillations corresponds to states of increased responsiveness of the neurons to peripheral stimulation. The sensory filtering role of the inferior olivary nucleus invites comparison between the cerebellum and cerebellar-like structures. This comparison sheds important light on the function of the cerebellum.

Indexed as

Afferent PathwaysAnimalsBiological ClocksCerebellumHumansModels, NeurologicalNeural InhibitionOlivary NucleusPresynaptic TerminalsSynaptic Transmission

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.