ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2003
Topographic plasticity in primary visual cortex is mediated by local corticocortical connections.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Macaque Area V2/V3 Reorganization Following Homonymous Retinal Lesions.Frontiers in neuroscience · 2022Article
- NGF Eye Administration Recovers the TrkB and Glutamate/GABA Marker Deficit in the Adult Visual Cortex Following Optic Nerve Crush.International journal of molecular sciences · 2021Article
- Changes in Prefrontal Cortex-Thalamic Circuitry after Acoustic Trauma.Biomedicines · 2021Article
- Mesoscopic cortical network reorganization during recovery of optic nerve injury in GCaMP6s mice.Scientific reports · 2020Article
- Rapid topographic reorganization in adult human primary visual cortex (V1) during noninvasive and reversible deprivation.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Time course of cytochrome oxidase blob plasticity in the primary visual cortex of adult monkeys after retinal laser lesions.The Journal of comparative neurology · 2019Article
- Preserved evoked conscious perception of phosphenes with direct stimulation of deafferented primary visual cortex.Epilepsy & behavior case reports · 2019Article
- Homeostatic plasticity in human extrastriate cortex following a simulated peripheral scotoma.Experimental brain research · 2017Article
- Cholinergic Potentiation of Restoration of Visual Function after Optic Nerve Damage in Rats.Neural plasticity · 2017Article
- Intracortical and Thalamocortical Connections of the Hand and Face Representations in Somatosensory Area 3b of Macaque Monkeys and Effects of Chronic Spinal Cord Injuries.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Regional Specificity of GABAergic Regulation of Cross-Modal Plasticity in Mouse Visual Cortex after Unilateral Enucleation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Precise visuotopic organization of the blind spot representation in primate V1.Journal of neurophysiology · 2015Article
- Adult cortical plasticity studied with chronically implanted electrode arrays.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Visual system plasticity in mammals: the story of monocular enucleation-induced vision loss.Frontiers in systems neuroscience · 2015Review
- Large-scale axonal reorganization of inhibitory neurons following retinal lesions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Quantification of early stages of cortical reorganization of the topographic map of V1 following retinal lesions in monkeys.Cerebral cortex (New York, N.Y. : 1991) · 2014Article
- Association between rates of binocular visual field loss and vision-related quality of life in patients with glaucoma.JAMA ophthalmology · 2013Article
- Tuning shifts of the auditory system by corticocortical and corticofugal projections and conditioning.Neuroscience and biobehavioral reviews · 2012Review
- Article
- Receptive Field Remodeling Induced by Skin Stimulation in Cerebellar Neurons in vivo.Frontiers in neural circuits · 2011Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The placement of monocular laser lesions in the adult cat retina produces a lesion projection zone (LPZ) in primary visual cortex (V1) in which the majority of neurons have a normally located receptive field (RF) for stimulation of the intact eye and an ectopically located RF (displaced to intact retina at the edge of the lesion) for stimulation of the lesioned eye. Animals that had such lesions for 14-85 d were studied under halothane and nitrous oxide anesthesia with conventional neurophysiological recording techniques and stimulation of moving light bars. Previous work suggested that a candidate source of input, which could account for the development of the ectopic RFs, was long-range horizontal connections within V1. The critical contribution of such input was examined by placing a pipette containing the neurotoxin kainic acid at a site in the normal V1 visual representation that overlapped with the ectopic RF recorded at a site within the LPZ. Continuation of well defined responses to stimulation of the intact eye served as a control against direct effects of the kainic acid at the LPZ recording site. In six of seven cases examined, kainic acid deactivation of neurons at the injection site blocked responsiveness to lesioned-eye stimulation at the ectopic RF for the LPZ recording site. We therefore conclude that long-range horizontal projections contribute to the dominant input underlying the capacity for retinal lesion-induced plasticity in V1.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.