ArticleJournal of feline medicine and surgery2003
Cardiac troponin I in cats with hypertrophic cardiomyopathy.
Article in Journal of feline medicine and surgery, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Effects of a resveratrol-containing nutraceutical on cardiac biomarkers, echocardiographic parameters, and oxidative stress in dogs with naturally occurring cardiac disease.Frontiers in veterinary science · 2026Article
- Linking clinical and imaging diagnostic assessments of the feline hypertrophic cardiomyopathy phenotype.Frontiers in veterinary science · 2025Review
- Determination ofVeterinary and animal science · 2022Article
- Cardiac troponin I in healthy Norwegian Forest Cat, Birman and domestic shorthair cats, and in cats with hypertrophic cardiomyopathy.Journal of feline medicine and surgery · 2022Article
- Prognostic Value of Neutrophil-to-Lymphocyte Ratio in Cats With Hypertrophic Cardiomyopathy.Frontiers in veterinary science · 2022Article
- The Feline Cardiomyopathies: 2. Hypertrophic cardiomyopathy.Journal of feline medicine and surgery · 2021Article
- Updates on Laboratory Evaluation of Feline Cardiac Diseases.Veterinary sciences · 2021Review
- Identifying Cardiac Diseases using Cardiac Biomarkers in Rhesus Macaques (Comparative medicine · 2020Article
- Biomarker changes with systolic anterior motion of the mitral valve in cats with hypertrophic cardiomyopathy.Journal of veterinary internal medicine · 2020Article
- Evaluation of a sensitive cardiac troponin I assay as a screening test for the diagnosis of hypertrophic cardiomyopathy in cats.Journal of veterinary internal medicine · 2019Article
- Diagnostic utility of cardiac troponin I in cats with hypertrophic cardiomyopathy.Journal of veterinary internal medicine · 2018Article
- A One Health Approach to Hypertrophic Cardiomyopathy.The Yale journal of biology and medicine · 2017Review
- Sleeping and resting respiratory rates in healthy adult cats and cats with subclinical heart disease.Journal of feline medicine and surgery · 2014Article
- Echocardiographic assessment of coronary artery flow in normal canines and model dogs with myocardial infarction.Journal of veterinary science · 2014Article
- Feline myocardial disease 2: diagnosis, prognosis and clinical management.Journal of feline medicine and surgery · 2009Review
- Cardiac troponin I levels in canine pyometra.Acta veterinaria Scandinavica · 2007Article
- Serum troponin I levels in hyperthyroid cats before and after treatment with radioactive iodine.Journal of feline medicine and surgery · 2005Article
- Cardiac Troponins in Dogs and Cats.Journal of veterinary internal medicineReview
- Plasma cardiac troponin I concentration and cardiac death in cats with hypertrophic cardiomyopathy.Journal of veterinary internal medicineArticle
- Cardiac biomarkers in hyperthyroid cats.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The molecular structure of cardiac troponin I (cTnI) is highly conserved across mammalian species and assays developed for its measurement in human patients have been validated in a number of veterinary species. A raised concentration of circulating cTnI is a sensitive and specific marker of cardiac myocyte injury. Raised levels have been documented in a variety of cardiac diseases in both human and veterinary patients. This study compared serum cTnI concentrations between 16 cats diagnosed with hypertrophic cardiomyopathy (HCM) using echocardiography and 18 control cats. The results show that cats with HCM have significantly higher concentration of serum cTnI (median 0.95 ng/ml, range 0.2-4.1 ng/ml) than control cats (median <0.2 ng/ml, range <0.2-0.25 ng/ml) [P<0.0001]. Furthermore in cats with cardiomyopathy a weak correlation was found between the thickness of the left ventricular freewall in diastole measured by ultrasound and serum cTnI concentration (r(2)=0.28;P=0.036). These results suggest that measurement of serum cTnI concentration may enable cats with cardiomyopathy to be distinguished from normal cats using the assay described here.
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