ArticleGenetics2003
Genetic variability at neutral markers, quantitative trait land trait in a subdivided population under selection.
Article in Genetics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
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Who cites it
81 citing papers in PubMed.
- Effect of population structure and stabilizing selection on quantitative genetic variation.Genetics · 2026Article
- Genomic forecasting for climate-resilient fruit trees.The New phytologist · 2026Review
- Why conserve genetic diversity? A perspective based on a case study with a European conifer.Annals of botany · 2026Article
- When South Meets North: A Joint Contact Zone Coinciding With Environmental Gradients in Three Boreal Tree Species.Molecular ecology · 2026Article
- Contrasting Patterns of Local Adaptation and Adaptive Potential Under Climate Change for Old-Growth and Planted Stands of Norway Spruce (Evolutionary applications · 2026Article
- Interpreting SNP heritability in admixed populations.Genetics · 2025Article
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- Interpreting SNP heritability in admixed populations.bioRxiv : the preprint server for biology · 2025Article
- Article
- Within- and between-population comparisons suggest independently acting selection maintaining parallel clines in Scots pine (Evolution letters · 2024Article
- A polygenic basis for birth weight in a wild population of red deer (Cervus elaphus).G3 (Bethesda, Md.) · 2023Article
- Article
- Population differentiation of polygenic score predictions under stabilizing selection.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Interactions between microenvironment, selection and genetic architecture drive multiscale adaptation in a simulation experiment.Journal of evolutionary biology · 2022Article
- Review
- Polygenic Selection within a Single Generation Leads to Subtle Divergence among Ecological NichesINc.Genome biology and evolution · 2021Article
- Identifying adaptive alleles in the human genome: from selection mapping to functional validation.Human genetics · 2021Review
- Divergent patterns between phenotypic and genetic variation in Scots pine.Plant communications · 2021Article
- Genetic Diversity, Structure and Effective Population Size of Old-Growth vs. Second-Growth Populations of Keystone and Long-Lived Conifer, Eastern White Pine (Frontiers in genetics · 2021Article
- High-Throughput Genome-Wide Genotyping To Optimize the Use of Natural Genetic Resources in the Grassland Species Perennial Ryegrass (G3 (Bethesda, Md.) · 2020Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic variability in a subdivided population under stabilizing and diversifying selection was investigated at three levels: neutral markers, QTL coding for a trait, and the trait itself. A quantitative model with additive effects was used to link genotypes to phenotypes. No physical linkage was introduced. Using an analytical approach, we compared the diversity within deme (H(S)) and the differentiation (F(ST)) at the QTL with the genetic variance within deme (V(W)) and the differentiation (Q(ST)) for the trait. The difference between F(ST) and Q(ST) was shown to depend on the relative amounts of covariance between QTL within and between demes. Simulations were used to study the effect of selection intensity, variance of optima among demes, and migration rate for an allogamous and predominantly selfing species. Contrasting dynamics of the genetic variability at markers, QTL, and trait were observed as a function of the level of gene flow and diversifying selection. The highest discrepancy among the three levels occurred under highly diversifying selection and high gene flow. Furthermore, diversifying selection might cause substantial heterogeneity among QTL, only a few of them showing allelic differentiation, while the others behave as neutral markers.
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