Evidence map›Paper›PMID 12865260›Full record

ArticleGut2003

Liver tolerance mediated by antigen presenting cells: fact or fiction?

A H Lau, A de Creus, L Lu, A W Thomson

Open access · bronzeAbstract read
In one paragraph

Article in Gut, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 36 citations in OpenAlex.

  1. LAMA4Cell communication and signaling : CCS · 2025
    Article
  2. In the Acute Phase ofFrontiers in immunology · 2022
    Article
  3. Article
  4. What's new in clinical solid organ transplantation by 2013.World journal of transplantation · 2014
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Hepatic AAV gene transfer and the immune system: friends or foes?Molecular therapy : the journal of the American Society of Gene Therapy · 2010
    Article
  10. The role of Ifng in alterations in liver gene expression in a mouse model of fulminant autoimmune hepatitis.Liver international : official journal of the International Association for the Study of the Liver · 2009
    Article
  11. Article
  12. Recruitment of dendritic cells in human liver with metastases.Clinical & experimental metastasis · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

A H LauDepartment of Surgery, Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.
A de Creus
L Lu
A W Thomson
University of Pittsburgh Medical Center · US

Funding

RHESUS MONKEY DENDRITIC CELLS FOR TRANSPLANT TOLERANCEU01AI051698 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI THOMSON, ANGUS W · 2002 to 2011
$4.9M
GENE ENGINEERING OF DENDRITIC CELLS AND TRANSPLANTATIONR01AI041011 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI THOMSON, ANGUS W · 1997 to 2006
$1.5M
LIVER TRANSPLANTATION: THE ROLE OF DENDRITIC CELLSR01DK049745 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI THOMSON, ANGUS W · 1996 to 2005
$1.4M
NIAID NIH HHS AI41011NIAID NIH HHS AI/DK51698NIAID NIH HHS R01 AI041011NIDDK NIH HHS DK49745NIDDK NIH HHS R01 DK049745
6 · The paper itself

Abstract

Possible mechanisms by which liver antigen presenting cells (APC) may facilitate tolerance induction are discussed. Tolerance may be facilitated by a distinctive combination of factors, linked to the unique anatomical and microenvironmental features of the liver.

Indexed as

Antigen-Presenting CellsHumansImmune ToleranceLiver TransplantationTransplantation Immunology

Identifiers

PMID12865260
PMCPMC1773771
OpenAlexW2138868589

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.