ReviewImmunologic research2003
Genetic approaches to tyrosine kinase signaling pathways in the immune system.
Review in Immunologic research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- A roadmap for translational cancer glycoimmunology at single cell resolution.Journal of experimental & clinical cancer research : CR · 2022Review
- Imaging techniques for assaying lymphocyte activation in action.Nature reviews. Immunology · 2011Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The development of a productive immune response requires the carefully coordinated activation of lymphocytes through their cell-surface antigen receptors, surface immunoglobulin (Ig) on B cells and the T cell receptor (TCR) on T cells. Studies of mutant cell lines, gene-targeted mice and humans with inherited immunodeficiencies have demonstrated that tyrosine kinases are critical components of lymphocyte antigen-receptor-signaling pathways. Our laboratory is interested in the mechanisms by which modulation of signaling pathways involving tyrosine kinases and related signaling molecules can influence cell function and development. We have concentrated our attention on the genetic and biochemical dissection of signaling pathways in the immune system, and how altering these pathways can change responses to infectious disease. As a model system, we are examining the Tec family kinases and their roles in T lymphocyte development and function.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.