ArticleJournal of virology2003
Dissection of cauliflower mosaic virus transactivator/viroplasmin reveals distinct essential functions in basic virus replication.
Article in Journal of virology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Discovery and Evolutionary Analysis of a Novel Genus of Endogenous Pararetroviruses with Long Terminal Repeats.Genome biology and evolution · 2025Article
- Phosphorylation of a reinitiation supporting protein, RISP, determines its function in translation reinitiation.Nucleic acids research · 2021Article
- Cauliflower mosaic virus transactivator protein (TAV) can suppress nonsense-mediated decay by targeting VARICOSE, a scaffold protein of the decapping complex.Scientific reports · 2019Article
- Setting Up Shop: The Formation and Function of the Viral Factories ofFrontiers in plant science · 2017Review
- Article
- Mutations within A 35 amino acid region of P6 influence self-association, inclusion body formation, and Caulimovirus infectivity.Virology · 2015Article
- Article
- Identification of the domains of cauliflower mosaic virus protein P6 responsible for suppression of RNA silencing and salicylic acid signalling.The Journal of general virology · 2013Article
- Cauliflower mosaic virus major inclusion body protein interacts with the aphid transmission factor, the virion-associated protein, and gene VII product.Virus research · 2012Article
- Cauliflower mosaic virus protein P6 inhibits signaling responses to salicylic acid and regulates innate immunity.PloS one · 2012Article
- Top 10 plant viruses in molecular plant pathology.Molecular plant pathology · 2011Review
- Viral factor TAV recruits TOR/S6K1 signalling to activate reinitiation after long ORF translation.The EMBO journal · 2011Article
- A new plant protein interacts with eIF3 and 60S to enhance virus-activated translation re-initiation.The EMBO journal · 2009Article
- The CaMV transactivator/viroplasmin interferes with RDR6-dependent trans-acting and secondary siRNA pathways in Arabidopsis.Nucleic acids research · 2008Article
- Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD.The EMBO journal · 2008Article
- A coiled-coil interaction mediates cauliflower mosaic virus cell-to-cell movement.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- The open reading frame VI product of Cauliflower mosaic virus is a nucleocytoplasmic protein: its N terminus mediates its nuclear export and formation of electron-dense viroplasms.The Plant cell · 2005Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cauliflower mosaic virus (CaMV) transactivator/viroplasmin (Tav) is an essential multifunctional viral protein. Dissection of Tav by deletion mutagenesis revealed that the central region is essential for CaMV replication in single cells but that the N- and C-terminal parts are not. Strains with mutations in the central region were defective in the translational transactivator function and could be complemented by coexpressing Gag (capsid protein precursor) and Pol (polyprotein with protease, reverse transcriptase, and RNase H activity) from separate monocistronic plasmids. In contrast, total omission of Tav was only partially complemented by Gag and Pol overexpression from separate plasmids. These results indicate that CaMV basic replication requires both Tav-activated polycistronic translation and some posttranslational function(s) of Tav that is not affected by the deletions in the central region of Tav.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.