Evidence map›Paper›PMID 12856082›Full record

SynthesisDiabetologia2003

Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus.

N G Boulé, G P Kenny, E Haddad, G A Wells, R J Sigal

2 registry-linked trialsAbstract readComparative StudyMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Diabetologia, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 199 papers, 30 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
199citing papers in PubMed, 30 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00284609 nacompletednot on this mapstarted 2006, after this paper: background citation

"The Effect of Rehabilitation of Type 2 Diabetes Mellitus Versus Standard Outpatient Care." A Randomized Controlled Trial.

TypeinterventionalSponsorBispebjerg HospitalRan2006 to 2010Enrolled180ConditionsType 2 Diabetes MellitusArmsGroup based non-pharmacological rehabilitation, Individual non-pharmacological rehabilitation
NCT03717363 nacompletednot on this mapstarted 2014, after this paper: background citation

Efficacy of Training Programme in Physical Activity Promotion in Patients With High Risk of Cardiovascular Disease

TypeinterventionalSponsorHospital Mutua de TerrassaRan2014 to 2017Enrolled147ConditionsCardiovascular Risk Factor, Cardiovascular DiseaseArmsTraining programme, Educational talk
3 · Its place in the literature

Who cites it

199 citing papers in PubMed, 30 syntheses or guidelines pooled it.

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  9. American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan-2022 Update.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2022
    Guideline
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139 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

N G BouléSchool of Human Kinetics, University of Ottawa, Ottawa, Ontario, Canada.
G P Kenny
E Haddad
G A Wells
R J Sigal

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aims/hypothesisLow cardiorespiratory fitness is a powerful and independent predictor of mortality in people with diabetes. Several studies have examined the effects of exercise on cardiorespiratory fitness in Type 2 diabetic individuals. However, these studies had relatively small sample sizes and highly variable results. Therefore the aim of this study was to systematically review and quantify the effects of exercise on cardiorespiratory fitness in Type 2 diabetic individuals.

methodsMEDLINE, EMBASE, and four other databases were searched up to March 2002 for randomized, controlled trials evaluating effects of structured aerobic exercise interventions of 8 weeks or more on cardiorespiratory fitness in adults with Type 2 diabetes. Cardiorespiratory fitness was defined as maximal oxygen uptake (VO(2max)) during a maximal exercise test.

resultsSeven studies, presenting data for nine randomized trials comparing exercise and control groups (overall n=266), met the inclusion criteria. Mean exercise characteristics were as follows: 3.4 sessions per week, 49 min per session for 20 weeks. Exercise intensity ranged from 50% to 75% of VO(2max). There was an 11.8% increase in VO(2max) in the exercise group and a 1.0% decrease in the control group (post intervention standardized mean difference =0.53, p<0.003). Studies with higher exercise intensities tended to produce larger improvements in VO(2max). Exercise intensity predicted post-intervention weighted mean difference in HbA(1c) (r=-0.91, p=0.002) to a larger extent than did exercise volume (r=-0.46, p=0.26). CONCLUSIONS/

interpretationRegular exercise has a statistically and clinically significant effect on VO(2max) in Type 2 diabetic individuals. Higher intensity exercise could have additional benefits on cardiorespiratory fitness and HbA(1c).

Indexed as

Exercise TherapyPhysical FitnessRespiratory Physiological PhenomenaDatabases, FactualDiabetes Mellitus, Type 2ExerciseHumansMEDLINEMiddle AgedOxygen ConsumptionRandomized Controlled Trials as Topic

Identifiers

PMID12856082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.