Evidence map›Paper›PMID 12854159›Full record

ArticleWorld journal of gastroenterology2003

Polymorphism in transmembrane region of MICA gene and cholelithiasis.

Shou-Chuan Shih, Yann-Jinn Lee, Hsin-Fu Liu, Ching-Wen Dang, Shih-Chuan Chang, Shee-Chan Lin, Chin-Roa Kao

Abstract read
In one paragraph

Article in World journal of gastroenterology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shou-Chuan ShihDepartment of Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
Yann-Jinn Lee
Hsin-Fu Liu
Ching-Wen Dang
Shih-Chuan Chang
Shee-Chan Lin
Chin-Roa Kao

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo study the significance of polymorphism of MHC class I chain-related gene A (MICA) gene in patients with cholelithiasis.

methodsSubjects included 170 unrelated adults (83 males) with cholelithiasis and 245 randomly selected unrelated adults (130 males) as controls. DNA was extracted from peripheral leukocytes and analyzed for polymorphism of 5 alleles (A4, A5, A5.1, A6 and A9) of the MICA gene.

resultsThere was no significant difference in phenotype, allele, and genotype frequencies of any of the 5 alleles between cholelithiasis patients and controls.

conclusionThis study demonstrates that MICA alleles studied bear no relation to cholelithiasis.

Indexed as

Polymorphism, GeneticAsian PeopleCholelithiasisFamily HealthFemaleGene FrequencyGenotypeHistocompatibility Antigens Class IHumansMaleMiddle AgedPhenotypeRandom AllocationHistocompatibility Antigens Class IMHC class I-related chain A

Identifiers

PMID12854159
PMCPMC4615500

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.