Evidence map›Paper›PMID 12848341›Full record

ReviewJournal of bioenergetics and biomembranes2003

Regulation of dynamin by nucleoside diphosphate kinase.

Radhakrishnan Narayanan, Mani Ramaswami

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of bioenergetics and biomembranes, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Nm23/NDP kinases in hepatocellular carcinoma.Journal of bioenergetics and biomembranes · 2006
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Radhakrishnan NarayananDepartment of Molecular and Cellular Biology and ARL, Division of Neurobiology, University of Arizona, Tucson, Arizona 85721, USA. rnarayan@u.arizona.edu
Mani Ramaswami
University of Arizona · US

Funding

MOLECULAR MECHANISMS IN SYNAPTIC VESICLE RECYCLINGR01NS034889 · NINDS · UNIVERSITY OF ARIZONA · PI RAMASWAMI, MANI · 1997 to 2004
$1.5M
MOLECULAR MECHANISMS IN SYNAPTIC VESICLE RECYCLINGK02NS002001 · NINDS · UNIVERSITY OF ARIZONA · PI RAMASWAMI, MANI · 1997 to 2001
$116k
NINDS NIH HHS K02-NS02001NINDS NIH HHS NS34889
6 · The paper itself

Abstract

Nucleoside diphosphate (NDP) kinase is required for multiple cellular functions, including cell growth, motility, and differentiation, and its loss is associated with pathologies including tumor metastasis. A recent study has revealed a previously unknown function for NDP kinase as positive regulator of dynamin, a GTPase essential for endocytosis. In this review we describe the evidence that NDP kinase function is essential for endocytosis and also elaborate on a mechanism for NDP kinase regulation of dynamin. Recently documented interactions between endocytosis and cell signaling have revealed new insights into potential mechanisms of cancer. In this context, we discuss the possible relevance of NDP kinase and dynamin interaction for tumor suppression.

Indexed as

EndocytosisGene Expression Regulation, EnzymologicGene Expression Regulation, NeoplasticTranscriptional ActivationAnimalsCoenzymesDynaminsHumansModels, BiologicalMultienzyme ComplexesNeoplasmsNucleoside-Diphosphate KinaseCoenzymesDynaminsMultienzyme ComplexesNucleoside-Diphosphate Kinase

Identifiers

PMID12848341
OpenAlexW2299193220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.