Trial reportCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2003
A randomized controlled trial of a pharmacist consultation program for family physicians and their elderly patients.
Trial report in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 18 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 18 syntheses or guidelines pooled it, 192 citations in OpenAlex.
- Interventions to Address Potentially Inappropriate Prescribing for Older Primary Care Patients: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- Involving community pharmacists in interprofessional collaboration in primary care: a systematic review.BMC primary care · 2024Pooled it
- Interprofessional collaboration in primary care: what effect on patient health? A systematic literature review.BMC primary care · 2023Pooled it
- Medicines Related Problems (MRPs) Originating in Primary Care Settings in Older Adults - A Systematic Review.Journal of pharmacy practice · 2023Pooled it
- The effectiveness and cost of integrating pharmacists within general practice to optimize prescribing and health outcomes in primary care patients with polypharmacy: a systematic review.BMC primary care · 2023Pooled it
- Cost Effectiveness of Advanced Pharmacy Services Provided in the Community and Primary Care Settings: A Systematic Review.PharmacoEconomics · 2019Pooled it
- Impact of integrating pharmacists into primary care teams on health systems indicators: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019Pooled it
- Pharmacist services for non-hospitalised patients.The Cochrane database of systematic reviews · 2018Pooled it
- Interventions to improve the appropriate use of polypharmacy for older people.The Cochrane database of systematic reviews · 2018Pooled it
- A systematic review of the outcomes reported in trials of medication review in older patients: the need for a core outcome set.British journal of clinical pharmacology · 2017Pooled it
- Effectiveness of medication review: a systematic review and meta-analysis of randomized controlled trials.BMC family practice · 2017Pooled it
- [Effectiveness of interventions for improving drug prescribing in Primary Health Care].Atencion primaria · 2017Pooled it
- Impact of strategies to reduce polypharmacy on clinically relevant endpoints: a systematic review and meta-analysis.British journal of clinical pharmacology · 2016Pooled it
- A systematic review and meta-analysis of pharmacist-led fee-for-services medication review.British journal of clinical pharmacology · 2014Pooled it
- Pooled it
- Medication review and reconciliation with cooperation between pharmacist and general practitioner and the benefit for the patient: a systematic review.British journal of clinical pharmacology · 2012Pooled it
- Effect of outpatient pharmacists' non-dispensing roles on patient outcomes and prescribing patterns.The Cochrane database of systematic reviews · 2010Pooled it
- Does pharmacist-led medication review help to reduce hospital admissions and deaths in older people? A systematic review and meta-analysis.British journal of clinical pharmacology · 2008Pooled it
- Assessing feasibility of conducting medication review with follow-up among older adults at community pharmacy: a pilot randomised controlled trial.International journal of clinical pharmacy · 2024Trial
- Impact of medication therapy management (MTM) service model on multi-morbidity (MMD) patients with hypertension: a pilot RCT.BMC geriatrics · 2023Trial
6 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPharmacists can improve patient outcomes in institutional and pharmacy settings, but little is known about their effectiveness as consultants to primary care physicians. We examined whether an intervention by a specially trained pharmacist could reduce the number of daily medication units taken by elderly patients, as well as costs and health care use.
methodsWe conducted a randomized controlled trial in family practices in 24 sites in Ontario. We randomly allocated 48 randomly selected family physicians (69.6% participation rate) to the intervention or the control arm, along with 889 (69.5% participation rate) of their randomly selected community-dwelling, elderly patients who were taking 5 or more medications daily. In the intervention group, pharmacists conducted face-to-face medication reviews with the patients and then gave written recommendations to the physicians to resolve any drug-related problems. Process outcomes included the number of drug-related problems identified among the senior citizens in the intervention arm and the proportion of recommendations implemented by the physicians.
resultsAfter 5 months, seniors in the intervention and control groups were taking a mean of 12.4 and 12.2 medication units per day respectively (p = 0.50). There were no statistically significant differences in health care use or costs between groups. A mean of 2.5 drug-related problems per senior was identified in the intervention arm. Physicians implemented or attempted to implement 72.3% (790/1093) of the recommendations.
interpretationThe intervention did not have a significant effect on patient outcomes. However, physicians were receptive to the recommendations to resolve drug-related problems, suggesting that collaboration between physicians and pharmacists is feasible.
Indexed as
Identifiers
12847034PMC164937W2149964874What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.